Amino Acid Formula With Vitamins And Minerals Without Valine, Leucine And Isoleucine
Withdrawn MetabolicRestrictedNot applicable line 💬 consumer voice
Dietary management of Maple Syrup Urine Disease (MSUD).
4
Submissions
2014–20
On the record
—
ICER range
Cost-min
Cost basis
Decisions on record
- Meeting Nov 2021 Withdrawn Maple syrup urine disease (MSUD)
- Meeting Jul 2021 Recommended Maple syrup urine disease
Access path
- Jul 2014Recommended · restricted
vs MSUD Aid III
- Nov 2014Deferred
- Nov 2019Recommended · restricted
- Jul 2020Recommended · restricted
Comparator changed: MSUD Gel → MSUD Express 20, MSUD Cooler 20, MSUD Lophlex LQ 20, MSUD…
- PBS listing · Restricted
RecommendedDeferredNot recommended
From the public summary
PBAC outcome
7.1 The PBAC recommended the Restricted Benefit listing of amino acid formula with vitamins and minerals without valine, leucine and isoleucine, MSUD Lophlex, for the management of MSUD on a cost-minimisation basis per gram of protein with the nominated comparators.PSD · Jul 2020
7.2 The PBAC noted that the NPWP accepted that MSUD Express 20, MSUD Cooler 20, MSUD Lophlex LQ 20 and MSUD Maxamum were relevant comparators.PSD · Jul 2020
Cost-effectiveness
Cost-minimisation analysis; no ICER calculated.
The PBAC recommended the Restricted Benefit listing of amino acid formula with vitamins and minerals without valine, leucine and isoleucine, MSUD Lophlex, for the management of MSUD on a cost-minimisation basis per gram of protein with the nominated comparators. PBAC · 2020
Cost-effectiveness accepted ×3
Decision context
PopulationPatients aged 3 years or over with Maple Syrup Urine Disease requiring dietary management.
Submission history
| Decided | Outcome | Comparator | ICER | Evidence |
|---|---|---|---|---|
| Jul 2020 | Recommended · restricted | MSUD Express 20, MSUD Cooler 20, MSUD Lophlex LQ 20, MSUD Maxamum | — | Cost-minimisation · Cost-minimisation |
| Nov 2019 | Recommended · restricted | MSUD Gel | — | Cost-minimisation · Cost-minimisation |
| Nov 2014 | Deferred | — | — | Cost-minimisation |
| Jul 2014 | Recommended · restricted | MSUD Aid III | — | Cost-minimisation · Cost-minimisation |
Consumer voice
The PBAC noted that no consumer comments were received for this item.
The PBAC noted that no consumer comments were received for this item. Consumer comments · PSD
Similar precedents
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Regulatory · TGA
Label narrower than PBS population — PBAC restricts to patients aged 3 years or over; TGA label does not specify age limits.