Amino Acid Formula With Fat, Carbohydrate, Without Valine, Leucine And Isoleucine
Recommended · restricted MetabolicRestrictedNot applicable line
Dietary management of maple syrup urine disease (MSUD).
1
Submissions
2019–19
On the record
—
ICER range
Cost-min
Cost basis
Access path
- Nov 2019Recommended · restricted
vs MSUD Express 20
- PBS listing · Restricted
RecommendedDeferredNot recommended
From the public summary
PBAC outcome
7.1 The PBAC recommended the Restricted Benefit listing of the amino acid formula, MSUD Easy® for the dietary management of maple syrup urine disease (MSUD) on a cost minimisation basis to the cheapest currently listed amino acid formula for the treatment of MSUD at an equivalent cost per gram of protein equivalent (PE).PSD · Nov 2019
7.2 The PBAC noted the NPWP supported the proposed listing as a treatment option for the dietary management of MSUD. The PBAC also noted the NPWP advice that MSUD Easy does not contain any vitamins, minerals or trace elements and that therefore patients would have to meet their dietary needs through other sources, which may include use of PBS-subsidised vitamin, mineral and trace element supplements included Phlexy-vits and Paediatric Seravit.PSD · Nov 2019
Cost-effectiveness
Cost-minimisation analysis; no ICER calculated. Priced per gram of protein equivalent equivalent to comparator.
The PBAC recommended the Restricted Benefit listing of the amino acid formula, MSUD Easy® for the dietary management of maple syrup urine disease (MSUD) on a cost minimisation basis to the cheapest currently listed amino acid formula for the treatment of MSUD at an equivalent cost per gram of protein equivalent (PE). PBAC · 2019
Cost-effectiveness accepted
Decision context
PopulationPatients with maple syrup urine disease (MSUD) requiring dietary management.
Submission history
| Decided | Outcome | Comparator | ICER | Evidence |
|---|---|---|---|---|
| Nov 2019 | Recommended · restricted | MSUD Express 20 | — | Cost-minimisation · Cost-minimisation |
Similar precedents
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Regulatory · TGA
Label equal than PBS population — Both TGA label and PBAC recommendation cover dietary management of MSUD in patients with the condition; no restriction applied.