Amino acid formula with fat, carbohydrate, without valine, leucine and isoleucine

PBAC's latest decision on Amino acid formula with fat, carbohydrate, without valine, leucine and isoleucine: Recommended (2019). Considered for Dietary management of maple syrup urine disease (MSUD).

Eligible population

Patients with maple syrup urine disease (MSUD) requiring dietary management.

Therapy area

Metabolic

Line of therapy

Not applicable

Evidence base

Cost-minimisation

Primary endpoint

Cost-minimisation

Comparator

MSUD Express 20

Economic model

Cost-minimisation

ICER note

Cost-minimisation analysis; no ICER calculated. Priced per gram of protein equivalent equivalent to comparator.

Similar precedents

• Amino acid formula with vitamins and minerals without valine, leucine and isoleucine
  similarity 0.86
• Amino acid formula with vitamins and minerals without valine, leucine, isoleucine, supplemented with arachidonic acid and docosahexaenoic acid
  similarity 0.81
• Amino acid formula with carbohydrate without phenylalanine
  similarity 0.75
• Amino acid formula without phenylalanine
  similarity 0.73
• Amino acid formula with vitamins and minerals (three formulations: without phenylalanine; without phenylalanine and tyrosine; without valine, leucine and isoleucine)
  similarity 0.74
• Amino acid formula with vitamins and minerals (msud, tyr, hcu coolers)
  similarity 0.74