Amino acid formula with vitamins and minerals (three formulations: without phenylalanine; without phenylalanine and tyrosine; without valine, leucine and isoleucine)
PBAC's latest decision on Amino acid formula with vitamins and minerals (three formulations: without phenylalanine; without phenylalanine and tyrosine; without valine, leucine and isoleucine): Recommended (2015). Considered for Nutritional management of phenylketonuria (PKU), tyrosinaemia, and maple syrup urine disease (MSUD) in children. These are formulation upgrades (pack size increase from 29 g to 36 g sachets, flavour change, and enhanced nutritional composition) of existing products.
PBAC outcome
Recommended
Authority Required
ICER (AUD/QALY)
Cost-min
cost-minimisation analysis
Submissions
1
first 2015
Submissions
1
2015 → 2015
Eligible population
Children requiring nutritional management of phenylketonuria, tyrosinaemia, or maple syrup urine disease.
Therapy area
Metabolic
Line of therapy
Not applicable
Evidence base
Cost-minimisation
Primary endpoint
Cost-minimisation
Comparator
Existing formulations in 29 g sachets
Economic model
Cost-minimisation
ICER note
Cost-minimisation analysis: new formulations priced on equivalent gram of protein basis to existing formulations.