Amino Acid Formula With Vitamins And Minerals Without Phenylalanine And Tyrosine
Dietary management of tyrosinaemia.
Decisions on record
- Meeting Jul 2021 Recommended Tyrosinaemia
- Meeting Mar 2012 Recommended Medicinal food no PSD
- Meeting Jul 2007 Recommended Food no PSD
- Meeting Mar 2003 Recommended A food for an inborn error of metabolism no PSD
- Meeting Sep 2002 Recommended A food for inborn errors of metabolism no PSD
Access path
- Nov 2014Deferred
- Jul 2016Recommended · restricted
Evidence: Other → Cost-minimisation
- Mar 2017Recommended · restricted
Comparator changed: TYR Express 15® → TYR Express15
- Jul 2020Recommended · restricted
Comparator changed: TYR Express15 → TYR Express 20, TYR Cooler 20, TYR Lophlex LQ, XPHEN…
- PBS listing · Restricted
From the public summary
7.1 The PBAC recommended the Restricted Benefit listing of amino acid formula with vitamins and minerals without phenylalanine and tyrosine, TYR Lophlex, for the management of tyrosinaemia (TYR) on a cost-minimisation basis per gram of protein with the nominated comparators.PSD · Jul 2020
7.2 The PBAC noted that the NPWP accepted TYR Express 20, TYR Cooler 20, TYR Lophlex LQ and XPHEN TYR Maxamum were relevant comparators.PSD · Jul 2020
Cost-effectiveness
Cost-minimisation analysis; no ICER calculated. PBAC recommended on a cost-minimisation basis per gram of protein with nominated comparators.
The PBAC recommended the Restricted Benefit listing of amino acid formula with vitamins and minerals without phenylalanine and tyrosine, TYR Lophlex, for the management of tyrosinaemia (TYR) on a cost-minimisation basis per gram of protein with the nominated comparators. PBAC · 2020
Decision context
PopulationPatients with tyrosinaemia aged 3 years or over (age restriction not required by PBAC due to specialist/nutritionist prescribing and product formulation).
Submission history
| Decided | Outcome | Comparator | ICER | Evidence |
|---|---|---|---|---|
| Jul 2020 | Recommended · restricted | TYR Express 20, TYR Cooler 20, TYR Lophlex LQ, XPHEN TYR Maxamum | — | Cost-minimisation · Cost-minimisation |
| Mar 2017 | Recommended · restricted | TYR Express15 | — | Cost-minimisation · Cost-minimisation |
| Jul 2016 | Recommended · restricted | TYR Express 15® | — | Cost-minimisation · Cost-minimisation |
| Nov 2014 | Deferred | — | — | Other |
Consumer voice
No consumer comments were received for this item.
The PBAC noted that no consumer comments were received for this item. Consumer comments · PSD
Similar precedents
Regulatory · TGA
Label narrower than PBS population — PBAC restricts to patients aged 3 years or over; TGA label does not specify age limits.
Listed in law
PBS listings commencing 1 Mar 2021 were made by these 4 determinations under the National Health Act 1953. A determination covers every listing that commenced that day, so this is the legal instrument in force for the date — not a document naming this medicine. Open it and check.
| Determination | Made | Status | |
|---|---|---|---|
| PB 13 of 2021 | 24 Feb 2021 | Repealed | PDF ↗ |
| PB 13 of 2021 | 24 Feb 2021 | Repealed | PDF ↗ |
| PB 14 of 2021 | 24 Feb 2021 | Repealed | PDF ↗ |
| PB 15 of 2021 | 24 Feb 2021 | Repealed | PDF ↗ |