Amino acid formula with vitamins and minerals without phenylalanine and tyrosine

PBAC's latest decision on Amino acid formula with vitamins and minerals without phenylalanine and tyrosine: Recommended with restriction (2020). Considered for Dietary management of tyrosinaemia.

Eligible population

Patients with tyrosinaemia aged 3 years or over (age restriction not required by PBAC due to specialist/nutritionist prescribing and product formulation).

Therapy area

Metabolic

Line of therapy

Not applicable

Evidence base

Cost-minimisation

Primary endpoint

Cost-minimisation

Comparator

TYR Express 20, TYR Cooler 20, TYR Lophlex LQ, XPHEN TYR Maxamum

Economic model

Cost-minimisation

ICER note

Cost-minimisation analysis; no ICER calculated. PBAC recommended on a cost-minimisation basis per gram of protein with nominated comparators.

Submission history

• Nov 2014: Deferred · Not applicable
• Jul 2016: Recommended with restriction · Restricted
• Mar 2017: Recommended with restriction · Restricted
• Jul 2020: Recommended with restriction · Restricted

Similar precedents

• Amino acid formula with fat, carbohydrate without phenylalanine and tyrosine
  similarity 0.83
• Amino acid formula with vitamins and minerals, without phenylalanine and tyrosine, supplemented with arachidonic acid and docosahexaenoic acid
  similarity 0.84
• Amino acid formula with vitamins and minerals (three formulations: without phenylalanine; without phenylalanine and tyrosine; without valine, leucine and isoleucine)
  similarity 0.80
• Glycomacropeptide and essential amino acids with vitamins and minerals
  similarity 0.75
• Amino acid formula with vitamins and minerals, without phenylalanine
  similarity 0.75
• Amino acid formula with vitamins and minerals without phenylalanine
  similarity 0.74