Disease index

type 2 diabetes

Endocrinology · 2005–2026

108decisions
42medicines
21carried consumer input
255individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
tirzepatide Treatment of adults with type 2 diabetes mellitus inadequately controlled with metformin, sulfonylurea, and/or insulin, who have failed or are… Mar 2026 Recommended with restriction 115 individuals
tirzepatide Treatment of adults with type 2 diabetes mellitus that is inadequately controlled despite use of metformin, sulfonylurea, and/or insulin, or in patients with… Jul 2025 Deferred 115 individuals
pioglitazone Treatment of type 2 diabetes mellitus (T2DM). The submission requested listing of new 30-pack sizes of pioglitazone tablets (15 mg, 30 mg, and 45 mg strengths)… May 2025 Recommended none received
dapagliflozin with sitagliptin Treatment of patients with Type 2 diabetes mellitus with inadequate response to dual therapy with metformin and either a SGLT2 inhibitor or a DPP4 inhibitor,… Mar 2024 Recommended with restriction input received
semaglutide Type 2 diabetes mellitus (T2DM). New strength (2 mg in 3 mL pre-filled pen) for initial treatment and continuing treatment, as a substitute formulation for the… Nov 2024 Recommended with restriction 5 individuals
tirzepatide Treatment of adults with inadequately controlled type 2 diabetes mellitus who have comorbid severe obesity or identify as Aboriginal and Torres Strait… Nov 2024 Not recommended 14 individuals
tirzepatide Treatment of adult patients with inadequately controlled type 2 diabetes as dual therapy in combination with metformin. Jul 2023 Not recommended 2 individuals
semaglutide Type 2 diabetes, available on the PBS for use in combination with metformin and/or sulfonylurea or with insulin. This submission relates to temporary supply of… Aug 2022 Recommended with restriction no section in document
dulaglutide Type 2 diabetes mellitus in patients who require treatment intensification to achieve glycaemic targets as dual therapy with metformin, specifically in those… May 2022 Recommended 1 individuals Diabetes Australia
dulaglutide Treatment of type 2 diabetes. The submission concerns temporary supply of an overseas-sourced version to address shortage caused by increased demand due to… Oct 2022 Recommended with restriction no section in document
semaglutide Treatment of Type 2 Diabetes Mellitus in combination with insulin and metformin (unless contraindicated or not tolerated) in patients with inadequate glycaemic… Mar 2021 Recommended with restriction input received
dulaglutide Type 2 diabetes mellitus in combination with insulin and metformin (unless contraindicated or not tolerated). Jul 2020 Recommended none received
semaglutide Treatment of adults with Type 2 Diabetes Mellitus with inadequate glycaemic control as dual therapy in combination with metformin or a sulfonylurea where… Mar 2020 Recommended none received
exenatide Type 2 diabetes mellitus in patients with inadequate glycaemic control on metformin and/or a sulfonylurea, for use as second- or third-line therapy. Mar 2019 Not recommended none received
insulin glargine with lixisenatide Treatment of adults with Type 2 diabetes mellitus who have inadequate glycaemic control with basal insulin, in combination with metformin or where metformin is… Mar 2019 Not recommended 1 individuals
dulaglutide Type 2 diabetes mellitus in patients with inadequate glycaemic control despite treatment with insulin (and metformin, if not contraindicated or not tolerated),… Nov 2019 Deferred input received
semaglutide Treatment of patients with type 2 diabetes who have inadequate glycaemic control, as dual therapy in combination with metformin or a sulfonylurea where either… Nov 2019 Recommended input received
ertugliflozin Type 2 diabetes mellitus in patients inadequately controlled with metformin or a sulfonylurea, for dual oral therapy with metformin or a sulfonylurea (15 mg… Jul 2018 Recommended with restriction none received
ertugliflozin with sitagliptin Type 2 diabetes mellitus in patients inadequately controlled on dual oral therapy with metformin and a dipeptidyl peptidase 4 inhibitor or sodium-glucose… Jul 2018 Recommended with restriction none received
ertugliflozin Type 2 diabetes mellitus in patients inadequately controlled with metformin or a sulfonylurea, for use in dual oral therapy with metformin or a sulfonylurea. Mar 2018 Recommended with restriction none received
insulin degludec with insulin aspart Treatment of adult patients with diabetes mellitus where insulin treatment is necessary. IDegAsp is indicated for improvement of glycaemic control in adult… Mar 2018 Recommended none received
insulin glargine with lixisenatide Type 2 diabetes mellitus in adults with inadequate glycaemic control with basal insulin, to be used in combination with metformin. Mar 2018 Not recommended input received Diabetes Australia
insulin glargine with lixisenatide Type 2 diabetes mellitus in patients with inadequate glycaemic control on basal insulin, in combination with metformin. Mar 2018 Not recommended input received Diabetes Australia
liraglutide Type 2 diabetes mellitus, specifically for dual combination therapy with metformin or a sulfonylurea, and triple combination therapy with metformin and a… Mar 2018 Not recommended none received
dapagliflozin with metformin Type 2 diabetes mellitus as triple oral therapy in combination with a dipeptidyl peptidase 4 (DPP4) inhibitor in patients uncontrolled on dual oral therapy. Jul 2017 Deferred none received
dapagliflozin Type 2 diabetes in adults with inadequate glycaemic control on dual therapy with metformin and a DPP4 inhibitor, as add-on triple oral therapy. Jul 2017 Deferred none received
dapagliflozin/saxagliptin Type 2 diabetes in adults with inadequate glycaemic control on dual therapy of metformin and a dipeptidyl peptidase 4 (DPP4) inhibitor. Jul 2017 Deferred none received
liraglutide Treatment of patients with Type 2 diabetes mellitus and high cardiovascular risk as dual therapy with metformin or a sulfonylurea, triple therapy with… Jul 2017 Not recommended input received
empagliflozin with linagliptin Type 2 diabetes mellitus as triple oral therapy in combination with metformin in patients intolerant or contraindicated to a combination of metformin and a… Mar 2017 Not recommended none received
dapagliflozin Type 2 Diabetes Mellitus in triple oral therapy with a dipeptidyl peptidase 4 inhibitor (DPP4 inhibitor/gliptin) and metformin in patients who have previously… Nov 2017 Recommended with restriction none received
dulaglutide Type 2 diabetes mellitus as dual therapy in combination with metformin and triple therapy in combination with metformin and sulfonylurea in patients not… Nov 2017 Recommended input received
empagliflozin, empagliflozin with metformin, linagliptin, linagliptin with metformin Type 2 Diabetes Mellitus in patients uncontrolled on dual oral therapy, for use in triple oral therapy (DPP4 inhibitor + SGLT2 inhibitor + metformin). Nov 2017 Recommended with restriction none received
empagliflozin with linagliptin Type 2 diabetes mellitus in patients uncontrolled on dual oral therapy with either a DPP4 inhibitor or SGLT2 inhibitor in combination with metformin; also for… Nov 2017 Recommended with restriction none received
vildagliptin Treatment of type 2 diabetes mellitus in patients not adequately controlled on insulin therapy with or without metformin, for use in combination with insulin. Nov 2017 Recommended with restriction none received
exenatide Type 2 diabetes mellitus in combination with metformin and/or a sulfonylurea in patients who have not achieved adequate glycaemic control. Mar 2016 Recommended with restriction no section in document
linagliptin Type 2 diabetes mellitus as triple oral therapy in combination with metformin and a sulfonylurea when dual therapy does not provide adequate glycaemic control. Mar 2016 Recommended with restriction none received
linagliptin Type 2 diabetes in combination with insulin, with or without metformin, when therapy with insulin (± metformin) does not provide adequate glycaemic control. Mar 2016 Recommended with restriction none received
vildagliptin Type 2 diabetes as triple oral combination therapy with metformin and a sulfonylurea when combination therapy with both agents does not provide adequate… Mar 2016 Recommended with restriction none received
dapagliflozin and metformin extended release Treatment of type 2 diabetes mellitus in adults as add-on to insulin therapy or as triple oral therapy in combination with a sulfonylurea. Jul 2015 Recommended no section in document
exenatide Type 2 diabetes mellitus as dual therapy (with metformin or a sulfonylurea) or triple therapy (with metformin and a sulfonylurea) in patients with HbA1c… Jul 2015 Recommended with restriction 1 individuals
saxagliptin and metformin extended release Extension of PBS indication for saxagliptin+metformin XR to include use in combination with a sulfonylurea (triple oral therapy) for the treatment of type 2… Jul 2015 Recommended none received
saxagliptin Treatment of patients with type 2 diabetes mellitus in combination with metformin and a sulfonylurea (triple oral therapy). Jul 2015 Recommended input received
sitagliptin Type 2 diabetes mellitus as part of triple oral therapy with metformin and a sulfonylurea when therapy with both agents does not provide adequate glycaemic… Jul 2015 Recommended none received
sitagliptin Treatment of type 2 diabetes mellitus in combination with insulin, with or without metformin. Jul 2015 Not recommended none received
dapagliflozin Type 2 diabetes mellitus in combination with metformin and a sulfonylurea (triple oral therapy). Mar 2015 Recommended input received
exenatide Type 2 diabetes mellitus in combination with insulin (basal insulin with or without metformin). Proposed as an alternative to insulin intensification with… Mar 2015 Recommended with restriction 1 individuals
empagliflozin Type 2 diabetes in combination with insulin, with or without metformin, when therapy with insulin (± metformin) does not provide adequate glycaemic control. Nov 2015 Recommended none received
empagliflozin/metformin Type 2 diabetes mellitus where metformin alone does not provide adequate glycaemic control. Empagliflozin/metformin fixed dose combination provides a treatment… Nov 2015 Recommended none received
sitagliptin Type 2 diabetes mellitus in combination with insulin, with or without metformin, in patients with inadequate glycaemic control despite insulin treatment with… Nov 2015 Not recommended none received
empagliflozin Type 2 diabetes mellitus as triple therapy in combination with metformin and a sulfonylurea when treatment with both agents does not provide adequate glycaemic… Nov 2015 Recommended none received
dapagliflozin and metformin extended release Treatment of type 2 diabetes in patients whose condition cannot be adequately controlled by metformin and a sulfonylurea, as a third-line therapy. Jul 2014 Recommended with restriction none received
dapagliflozin Diabetes mellitus type 2 (T2DM) in combination with metformin or a sulfonylurea when the condition cannot be adequately controlled by treatment with metformin… Jul 2014 Not recommended no section in document
empagliflozin Treatment of type 2 diabetes in combination with metformin or a sulfonylurea in patients unable to be adequately controlled by treatment with metformin and a… Jul 2014 Recommended with restriction none received
glucose indicator blood strip Blood glucose monitoring in patients receiving treatment under a GP Management Plan or Team Care Arrangements. Jul 2014 Recommended no section in document
lixisenatide Treatment of type 2 diabetes mellitus in combination with metformin (dual therapy) or in combination with metformin and a sulphonylurea (triple therapy). Jul 2014 Not recommended input received
lixisenatide Treatment of type 2 diabetes in combination with insulin, in patients with inadequate glycaemic control despite treatment with insulin and oral antidiabetic… Jul 2014 Not recommended none received
thiazolidinediones, glucagon-like peptide-1 receptor agonists, sodium-glucose co-transporter 2 inhibitors Third-line treatment of type 2 diabetes mellitus after failure of first and second-line treatment options. Jul 2014 Deferred no section in document
dapagliflozin Type 2 diabetes in combination with insulin in patients with inadequate glycaemic control despite treatment with insulin and oral antidiabetic agents, or… Nov 2014 Recommended input received
glucose indicator blood strip Blood glucose monitoring in patients receiving treatment under a GP Management Plan or Team Care Arrangements. Nov 2014 Recommended with restriction no section in document
alogliptin Type 2 diabetes mellitus in combination with metformin or a sulfonylurea in patients whose HbA1c is greater than 7% despite treatment with either metformin or… Jul 2013 Recommended with restriction no section in document
canagliflozin Type 2 diabetes mellitus as dual oral combination therapy with metformin or a sulfonylurea in patients whose HbA1c is greater than 7% despite treatment with… Jul 2013 Recommended with restriction no section in document
vildagliptin/metformin Type 2 diabetes mellitus as triple oral combination therapy (vildagliptin/metformin fixed-dose combination with a sulfonylurea) in patients with HbA1c greater… Jul 2013 Recommended no section in document
vildagliptin Type 2 diabetes mellitus as triple oral combination therapy with metformin and a sulfonylurea in patients whose HbA1c is greater than 7% despite maximally… Jul 2013 Not recommended no section in document
dapagliflozin Type 2 diabetes mellitus as dual oral combination therapy with metformin or a sulfonylurea in patients whose HbA1c is greater than 7% prior to initiation and… Jul 2013 Recommended with restriction no section in document
saxagliptin with metformin Type 2 diabetes mellitus in patients whose HbA1c is greater than 7% prior to initiation of a dipeptidyl peptidase 4 inhibitor, thiazolidinedione or… Apr 2013 Recommended no section in document
linagliptin with metformin hydrochloride Type 2 diabetes mellitus in patients with HbA1c >7% despite metformin monotherapy, where metformin-sulfonylurea combination is contraindicated or not… Mar 2013 Deferred no section in document
linagliptin with metformin hydrochloride Type 2 diabetes mellitus in patients with HbA1c greater than 7% despite treatment with metformin, where a combination of metformin and a sulfonylurea is… Mar 2013 Recommended no section in document
liraglutide Treatment of type 2 diabetes as dual combination therapy with metformin or a sulfonylurea in patients for whom a combination of metformin and a sulfonylurea is… Mar 2013 Recommended with restriction unclear
saxagliptin with metformin Type 2 diabetes mellitus in patients with HbA1c greater than 7% despite treatment with metformin, where a combination of metformin and a sulfonylurea is… Mar 2013 Deferred no section in document
alogliptin with metformin Type 2 diabetes mellitus in patients whose HbA1c is greater than 7% despite treatment with metformin, without requiring prior intolerance or contraindication… Nov 2013 Recommended with restriction no section in document
metformin and saxagliptin Treatment of type 2 diabetes mellitus in patients with HbA1c greater than 7% despite treatment with metformin, where a combination of metformin and a… Nov 2013 Recommended with restriction no section in document
metformin and sitagliptin Type 2 diabetes mellitus in patients whose HbA1c is greater than 7% despite treatment with metformin, for initiation of a dipeptidyl peptidase 4 inhibitor,… Nov 2013 Recommended no section in document
exenatide Type 2 diabetes mellitus in dual combination therapy with metformin or a sulfonylurea, or in triple combination therapy with metformin and a sulfonylurea, in… Nov 2013 Recommended with restriction no section in document
linagliptin Treatment of patients with type 2 diabetes in combination with metformin and a sulfonylurea (triple therapy) Jul 2012 Not recommended no section in document
saxagliptin Type 2 diabetes, in combination with insulin, in a patient whose HbA1c is greater than 7% prior to initiation of a dipeptidyl peptidase 4 inhibitor (gliptin),… Jul 2012 Not recommended no section in document
linagliptin Treatment of patients with type 2 diabetes in combination with metformin and a sulfonylurea (triple therapy) when HbA1c is greater than 7% despite maximally… Jul 2012 Not recommended no section in document
saxagliptin Treatment of type 2 diabetes in combination with insulin in patients whose HbA1c is greater than 7% despite treatment with insulin and oral anti-diabetic… Jul 2012 Not recommended no section in document
Dapagliflozin Type 2 diabetes in combination with metformin or a sulfonylurea. Mar 2012 Not recommended no section in document
dapagliflozin Type 2 diabetes, in combination with insulin, in a patient whose HbA1c is greater than 7% prior to initiation of a dipeptidyl peptidase 4 inhibitor (gliptin),… Mar 2012 Not recommended no section in document
dapagliflozin Type 2 diabetes mellitus in combination with metformin or a sulfonylurea, in patients whose HbA1c is greater than 7% despite treatment with either agent and… Mar 2012 Not recommended no section in document
dapagliflozin Type 2 diabetes, in combination with insulin, in a patient whose HbA1c is greater than 7% prior to initiation of a dipeptidyl peptidase 4 inhibitor (gliptin),… Mar 2012 Rejected no section in document
sitagliptin with simvastatin For use in patients with type 2 diabetes who are currently receiving treatment with simvastatin and who satisfy the criteria for prescribing DPP-4 inhibitors. Nov 2012 Recommended with restriction no section in document
sitagliptin with simvastatin Type 2 diabetes mellitus and hypercholesterolaemia in patients currently receiving treatment with simvastatin and who satisfy the criteria for prescribing… Nov 2012 Recommended with restriction no section in document
exenatide Type 2 diabetes mellitus in combination with metformin or a sulfonylurea, and in triple combination therapy with metformin and a sulfonylurea, in patients who… Jul 2011 Not recommended no section in document
linagliptin Type 2 diabetes, in combination with either metformin or a sulfonylurea, in a patient whose HbA1c is greater than 7% prior to initiation of a dipeptidyl… Jul 2011 Recommended no section in document
linagliptin Type 2 diabetes, in combination with either metformin or a sulfonylurea, in a patient whose HbA1c is greater than 7% prior to initiation of a dipeptidyl… Jul 2011 Recommended no section in document
liraglutide Dual combination therapy with metformin or a sulphonylurea in patients for whom a combination of metformin and a sulphonylurea is contraindicated or not… Nov 2011 Not recommended unclear
linagliptin Type 2 diabetes mellitus in combination with metformin or a sulfonylurea, in patients with HbA1c >7% despite treatment with either metformin or a sulfonylurea… Nov 2011 Recommended with restriction no section in document
saxagliptin Type 2 diabetes mellitus, in combination with metformin or a sulfonylurea, in a patient whose HbA1c is greater than 7 % despite treatment with either metformin… Mar 2010 Recommended with restriction no section in document
vildagliptin Type 2 diabetes mellitus in combination with metformin or a sulfonylurea, in a patient whose HbA1c is greater than 7% prior to initiation of a DPP-4 inhibitor… Mar 2010 Recommended with restriction no section in document
vildagliptin Type 2 diabetes mellitus in combination with metformin or a sulfonylurea in patients whose HbA1c is greater than 7% despite treatment with either agent alone,… Mar 2010 Recommended with restriction no section in document
liraglutide Type 2 diabetes mellitus patients as combination therapy with metformin and a sulfonylurea (triple therapy) or combination therapy with metformin or a… Nov 2010 Not recommended no section in document
exenatide Adjunctive therapy in patients with type 2 diabetes mellitus not achieving adequate glycaemic control despite optimal therapy with metformin and/or a… Mar 2008 Recommended no section in document
sitagliptin phosphate Type 2 diabetes mellitus in combination with metformin or a sulfonylurea, where HbA1c remains greater than 7% despite monotherapy and where combination with… Mar 2008 Recommended with restriction no section in document
exenatide Adjunctive therapy to improve glycaemic control in patients with type 2 diabetes mellitus who are taking metformin, a sulfonylurea or a combination of… Nov 2008 Recommended with restriction no section in document
exenatide Adjunctive therapy for adults with type 2 diabetes who are taking metformin, a sulfonylurea, or a combination of metformin and a sulfonylurea but are not… Jul 2007 Not recommended no section in document
exenatide Adjunctive therapy in patients with type 2 diabetes who are no longer achieving glycaemic control despite optimal therapy with metformin and/or a sulfonylurea. Jul 2007 Not recommended no section in document
Insulin detemir people with type 2 diabetes who are not responsive to oral hypoglycaemic drugs Nov 2007 Recommended with restriction no section in document
pioglitazone hydrochloride Triple oral combination therapy with metformin and a sulfonylurea for the treatment of type 2 diabetes mellitus in patients who have an HbA1c greater than 7%… Nov 2007 Recommended with restriction no section in document
Rosiglitazone maleate Type 2 diabetes, alone or in combination with other diabetes therapies, in a patient whose HbA1c is greater than 7% prior to initiation of a thiazolidinedione… Nov 2007 Not recommended no section in document
insulin detemir Extension of listing to include people with type 2 diabetes who are not responsive to oral hypoglycaemic drugs. Previously listed for type 1 diabetes. Nov 2007 Recommended with restriction no section in document
pioglitazone hydrochloride Type 2 diabetes mellitus in combination with metformin and a sulfonylurea in patients with HbA1c greater than 7% despite maximally tolerated doses of metformin… Nov 2007 Recommended with restriction no section in document
rosiglitazone maleate Type 2 diabetes mellitus, alone or in combination with other diabetes therapies, in patients whose HbA1c is greater than 7% prior to initiation of a… Nov 2007 Not recommended no section in document
rosiglitazone maleate with metformin hydrochloride type 2 diabetes mellitus, for use in combination therapy or as part of triple therapy when used in combination with a sulfonylurea, and for initiation of… Jul 2006 Recommended with restriction no section in document
rosiglitazone maleate with metformin hydrochloride Type 2 diabetes mellitus in patients with inadequate glycaemic control on metformin alone or in combination with a sulfonylurea, for dual therapy or triple… Jul 2006 Recommended with restriction no section in document
insulin detemir Treatment of Type 1 or Type 2 diabetes patients requiring intensive insulin therapy with 3 or more injections of insulin per day, and Type 1 patients with a… Mar 2006 Recommended with restriction no section in document
insulin glargine For the treatment of Type 1 diabetes; For the treatment of Type 2 diabetes when used in combination with three or more prandial doses of insulin per day; For… Mar 2006 Recommended no section in document
insulin detemir Treatment of diabetes mellitus where used as basal insulin in combination with meal-related short- or rapid-acting insulin. Jul 2005 Recommended no section in document

Who spoke

Diabetes Australia

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 21 of 59 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.