script.reportAU
Respiratory

Fluticasone furoate / vilanterol trifenatate

Brand: Breo Ellipta

PBAC's latest decision on Fluticasone furoate / vilanterol trifenatate: Recommended with restriction (2014). Considered for Regular treatment of asthma in adults and adolescents aged 12 years and older where use of a combination product (long-acting beta-2 agonist and inhaled corticosteroid) is appropriate.

PBAC outcome
Recommended with restriction
Restricted
ICER (AUD/QALY)
Cost-min
cost-minimisation analysis
Submissions
1
first 2014
Submissions
1
2014 → 2014

Eligible population

Adults and adolescents aged 12 years and older with asthma who are symptomatic on inhaled corticosteroids with 'as needed' short-acting beta-2 agonist, or already on both an inhaled corticosteroid and a long-acting beta-2 agonist.

Therapy area
Respiratory
Line of therapy
Any
Evidence base
RCT
Primary endpoint
PFS
Pivotal trial size
806 patients
Key trials
HZA113091, HZA106829, SFCB3019, SFCB3023
Comparator
fluticasone propionate/salmeterol (FP/SAL) fixed dose combination
Economic model
Cost-minimisation
ICER note
Cost minimisation analysis; no ICER calculated by design

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