Amino Acid Formula With Fat, Carbohydrate, Vitamins, Minerals, Trace Elements And Medium Chain Triglycerides
Amino acid formula for children with cows' milk protein enteropathy, severe cows' milk protein enteropathy with failure to thrive, combined intolerance to cows' milk protein/soy protein/protein hydrolysate formulae, IgE-mediated allergy to cows' milk and soy protein, eosinophilic oesophagitis, cows' milk anaphylaxis, and severe intestinal malabsorption including short bowel syndrome.
Decision on record
- Meeting Nov 2024 Recommended Combined intolerance to cows' milk protein, soy protein and protein hydrolysate formulae; severe intestinal malabsorption including short bowel syndrome; eosinophilic oesophagitis; cows' milk protein enteropathy; severe cows' milk protein enteropathy with failure to thrive; proven IgE-mediated aller
Access path
- Mar 2017Recommended · restricted
vs Alfamino Junior®
- Mar 2021Recommended · restricted
Comparator changed: Alfamino Junior® → Neocate Junior
- Nov 2024Recommended · restricted
Comparator changed: Neocate Junior → Essential Care Jr 800 g (primary); also Neocate…
- PBS listing · Authority Required
From the public summary
7.1 The PBAC recommended a General Schedule Authority Required (Telephone/Online) listing of a 400 g pouch of amino acid formula with fat, carbohydrate, vitamins, minerals, trace elements and medium chain triglycerides oral powder (Essential Care Jr) with a new formulation, for the same indications as the current PBS listings for the 800 g pouch of Essential Care Jr.PSD · Nov 2024
7.2 The PBAC considered that the new 400 g pack size of Essential Care Jr with the new formulation should be cost-minimised to the lowest cost comparator accepted by the NPWP (the current 800 g pack of Essential Care Jr, Neocate Junior, and Alfamino Junior) at an equivalent cost per kilojoule.PSD · Nov 2024
5.7 The submission did not present an economic analysis. The submission requested the same dispensed price for maximum quantity (DPMQ) of $336.55 as the currently PBS- listed Essential Care Jr 800 g.PSD · Nov 2024
5.8 In March 2021, the PBAC recommended Essential Care Jr 800 g on a cost-minimisation basis compared with Neocate Junior and Alfamino Junior at an equivalent cost per kilojoule at the March 2021 PBAC meeting (paragraph 7.01, Essential Care Jr, PSD, March 2021 PBAC meeting). The energy content and proposed price of Essential Care Jr 400 g in comparison to these products is presented in Table 2.PSD · Nov 2024
5.16 The PBAC noted the submission described Essential Care Jr as non-inferior in terms of both effectiveness and safety to Neocate Junior. The PBAC considered this was reasonable, on the basis that Essential Care Jr provides the same amount of energy in comparison to Neocate Junior.PSD · Mar 2021
5.2 The PBAC noted and welcomed the input from ausEE Inc. via the Consumer Comments facility on the PBS website. The comment supported the continuous supply and availability of Essential Care Jr and emphasized the importance of having a variety of amino acid formula options for children with Eosinophilic Oesophagitis and other PBS- listed indications. Nutritional profilePSD · Nov 2024
5.5 The sponsor provided comparisons of the new nutritional profile against the Australia New Zealand Food Standards Code Standard 2.9.1 Schedule 2 requirements and the Standard 2.9.5 Schedule 2 requirements as well as adequate intake (AI) and recommended daily intake (RDI) requirements.PSD · Nov 2024
Cost-effectiveness
Cost-minimisation analysis; no ICER calculated as submission was on cost-minimisation basis at equivalent cost per kilojoule
The PBAC considered that the new 400 g pack size of Essential Care Jr with the new formulation should be cost-minimised to the lowest cost comparator accepted by the NPWP (the current 800 g pack of Essential Care Jr, Neocate Junior, and Alfamino Junior) at an equivalent cost per kilojoule. PBAC · 2024
Decision context
PopulationChildren up to 24 months of age with cows' milk protein enteropathy, severe cows' milk protein enteropathy with failure to thrive, combined intolerance to cows' milk protein/soy protein/protein hydrolysate formulae, proven IgE-mediated allergy to cows' milk and soy protein, eosinophilic oesophagitis, cows' milk anaphylaxis, or severe intestinal malabsorption including short bowel syndrome, under specialist allergist, clinical immunologist, or specialist paediatric gastroenterologist and hepatologist management.
Submission history
| Decided | Outcome | Comparator | ICER | Evidence |
|---|---|---|---|---|
| Nov 2024 | Recommended · restricted | Essential Care Jr 800 g (primary); also Neocate Junior and Alfamino Junior | — | Cost-minimisation · Cost-minimisation |
| Mar 2021 | Recommended · restricted | Neocate Junior | — | Cost-minimisation · Cost-minimisation |
| Mar 2017 | Recommended · restricted | Alfamino Junior® | — | Cost-minimisation · Cost-minimisation |
Consumer voice
ausEE Inc. supported the continuous supply and availability of Essential Care Jr and emphasized the importance of having a variety of amino acid formula options for children with Eosinophilic Oesophagitis and other PBS-listed indications.
The comment supported the continuous supply and availability of Essential Care Jr and emphasized the importance of having a variety of amino acid formula options for children with Eosinophilic Oesophagitis and other PBS-listed indications. Consumer comments · PSD