Disease index

RCC

Oncology · 2006–2024

42decisions
14medicines
17carried consumer input
37individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
bevacizumab Metastatic colorectal cancer, locally recurrent or metastatic breast cancer, advanced/metastatic/recurrent non-squamous non-small cell lung cancer, advanced… Mar 2024 Recommended with restriction 1 individuals
cabozantinib Treatment of advanced renal cell carcinoma (RCC) in treatment-naïve adults with intermediate or poor risk and in adults following prior treatment with a… Mar 2024 Recommended input received ANZUP Cancer Trials Group · Rare Cancers Australia · Medical Oncology Group
cabozantinib Stage IV clear cell variant renal cell carcinoma (RCC) in patients who are classified as intermediate or poor risk according to the International Metastatic… Mar 2024 Recommended input received Rare Cancers Australia · Medical Oncology Group
pembrolizumab Adjuvant treatment of patients with renal cell carcinoma (RCC) with clear cell component who are at intermediate-high or high risk of recurrence following… Nov 2024 Recommended 4 individuals Rare Cancers Australia
pembrolizumab First-line treatment of advanced (Stage IV) clear cell variant renal cell carcinoma in patients classified as intermediate or poor risk according to IMDC… Mar 2022 Recommended with restriction input received Medical Oncology Group
avelumab First-line treatment of advanced (stage IV) clear cell variant renal cell carcinoma in patients classified as intermediate or poor risk according to IMDC… Mar 2021 Recommended unclear
avelumab First-line treatment of advanced (stage IV) clear cell variant renal cell carcinoma in patients with intermediate to poor prognostic risk according to IMDC… Mar 2020 Not recommended input received Rare Cancers Australia
cabozantinib Stage IV clear cell variant advanced renal cell carcinoma (RCC) with intermediate to poor risk classification according to IMDC criteria, in patients who have… Mar 2020 Not recommended input received Rare Cancers Australia · Medical Oncology Group
cabozantinib Stage IV clear cell variant advanced renal cell carcinoma (RCC) with intermediate to poor risk classification according to IMDC criteria in treatment-naïve… Nov 2020 Recommended with restriction input received Medical Oncology Group
cabozantinib First-line treatment of Stage IV clear cell variant renal cell carcinoma (RCC) in patients meeting IMDC criteria for intermediate to poor risk disease. Mar 2019 Not recommended unclear
nivolumab + ipilimumab First-line treatment of Stage IV clear cell variant renal cell carcinoma (RCC) in patients with intermediate to poor risk disease according to IMDC criteria… Jul 2018 Not recommended 7 individuals
lenvatinib Stage IV clear cell variant renal cell carcinoma (RCC) in patients who have progressed after first-line treatment with a tyrosine kinase inhibitor, for use in… Mar 2018 Not recommended none received
nivolumab First-line treatment of Stage IV clear cell variant renal cell carcinoma in patients meeting IMDC intermediate to poor risk group criteria. Nov 2018 Recommended with restriction input received
nivolumab Stage IV clear cell variant renal cell carcinoma (RCC) in patients who have progressed according to RECIST following first-line treatment with a… Mar 2017 Recommended with restriction 4 individuals
cabozantinib Treatment of patients with Stage IV (unresectable) clear cell variant renal cell carcinoma (RCC) with progressive disease following first-line treatment with a… Dec 2017 Recommended 1 individuals
lenvatinib Treatment of patients with stage IV clear cell variant renal cell carcinoma (RCC) whose disease has progressed following first-line tyrosine kinase inhibitor… Nov 2017 Not recommended none received
nivolumab Advanced or metastatic clear cell variant renal cell carcinoma (RCC) in patients who have progressed following first-line treatment with a tyrosine-kinase… Jul 2016 Not recommended 1 individuals
nivolumab Second-line treatment of Stage IV clear cell variant renal cell carcinoma (RCC) in patients with progressive disease following first-line tyrosine kinase… Nov 2016 Not recommended 7 individuals
everolimus Stage IV clear cell variant renal cell carcinoma (RCC) after disease progression following first-line treatment with a tyrosine kinase inhibitor. Mar 2014 Recommended with restriction 2 individuals
axitinib Second-line treatment of stage IV clear cell variant renal cell carcinoma (RCC) in patients with progressive disease following first-line tyrosine kinase… Nov 2014 Recommended with restriction 6 individuals
sorafenib Second-line treatment of stage IV clear cell variant renal cell carcinoma (advanced RCC) in patients who have failed first-line treatment with a tyrosine… Nov 2014 Recommended 4 individuals
axitinib Second-line treatment of Stage IV clear cell variant renal cell carcinoma in patients with WHO performance status of 2 or less where disease progression has… Nov 2013 Not recommended no section in document
sorafenib Stage IV (advanced) clear cell variant renal cell carcinoma as second-line treatment in patients who have failed first-line therapy with sunitinib or pazopanib… Nov 2013 Not recommended unclear
pazopanib Initial and continuing treatment as the sole PBS-subsidised tyrosine kinase inhibitor therapy for stage IV clear cell variant renal cell carcinoma (RCC) in a… Mar 2012 Recommended with restriction no section in document
pazopanib Initial and continuing treatment of stage IV clear cell variant renal cell carcinoma (RCC) in newly diagnosed patients meeting MSKCC low to intermediate risk… Mar 2012 Recommended with restriction no section in document
sorafenib initial and continuing treatment of Stage IV clear cell renal carcinoma in a patient who has failed therapy with first line treatment and meets certain… Nov 2012 Recommended no section in document
sorafenib Initial and continuing treatment of Stage IV clear cell renal carcinoma in patients who have failed first-line therapy with favourable or intermediate MSKCC… Nov 2012 Recommended no section in document
everolimus initial and continuing treatment of Stage IV clear cell variant renal cell carcinoma in a patient with a WHO status of 2 or less, who has failed treatment with… Nov 2011 Not recommended unclear
everolimus Initial and continuing treatment of Stage IV clear cell variant renal cell carcinoma in patients with WHO status 2 or less who have failed treatment with… Nov 2011 Not recommended unclear
everolimus Initial and continuing treatment of Stage IV clear cell variant renal cell carcinoma in a patient with a WHO status of 2 or less who has progressive disease on… Jul 2010 Not recommended no section in document
pazopanib treatment of stage IV advanced and/or metastatic, clear cell variant, renal cell carcinoma (RCC) in an adult patient who meets certain criteria Jul 2010 Not recommended no section in document
everolimus Initial and continuing treatment of Stage IV clear cell variant renal cell carcinoma in patients with WHO status ≤2 who have progressive disease on sunitinib… Jul 2010 Not recommended no section in document
pazopanib Treatment of stage IV advanced and/or metastatic, clear cell variant renal cell carcinoma (RCC) in adult patients who meet certain criteria. Jul 2010 Not recommended no section in document
everolimus Treatment of patients with Stage IV clear cell variant renal cell carcinoma after failure of treatment with sorafenib or sunitinib. Nov 2009 Not recommended no section in document
sunitinib malate treatment of advanced (unresectable or metastatic) renal cell carcinoma (RCC) in patients with an ECOG performance status of 0 or 1 Jul 2008 Recommended with restriction no section in document
temsirolimus treatment of advanced renal cell carcinoma (RCC) in patients with a poor prognosis who meet certain criteria Jul 2008 Recommended no section in document
sorafenib tosylate Initial and continuing treatment of advanced renal cell carcinoma in patients with WHO performance status 2 or less, with continuing treatment defined as… Mar 2008 Not recommended no section in document
sunitinib malate Treatment of advanced (unresectable or metastatic) renal cell carcinoma (RCC) in patients with an Eastern Cooperative Oncology Group (ECOG) performance status… Mar 2008 Not recommended no section in document
sunitinib malate treatment of advanced renal cell carcinoma (RCC) Mar 2007 Deferred no section in document
sunitinib malate Treatment of advanced renal cell carcinoma (RCC) as first-line therapy. Mar 2007 Deferred no section in document
sorafenib initial and continuing treatment of advanced renal cell carcinoma in patients with WHO performance status of 2 or less, and beyond 3 months for those with… Nov 2006 Recommended no section in document
sorafenib tosylate Initial and continuing treatment of advanced (unresectable or metastatic) renal cell carcinoma in patients with WHO performance status of 2 or less. Nov 2006 Recommended no section in document

Who spoke

Rare Cancers Australia · Medical Oncology Group · ANZUP Cancer Trials Group

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 17 of 21 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.