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Vaccines

Zoster virus vaccine live

Brand: Zostavax

PBAC's latest decision on Zoster virus vaccine live: Deferred (2014). Considered for Prevention of herpes zoster and post-herpetic neuralgia in immunocompetent people aged 70 years (ongoing cohort) and 71-79 years (catch-up cohort).

PBAC outcome
Deferred
Restricted
ICER (AUD/QALY)
Not modelled
no economic evaluation
Submissions
2
first 2014
Submissions
2
2014 → 2014

Eligible population

Immunocompetent people aged 70 years (ongoing cohort) and 71-79 years (catch-up cohort).

Therapy area
Vaccines
Line of therapy
Not applicable
Evidence base
RCT
Primary endpoint
Other
Pivotal trial size
38,546 patients
Key trials
SPS (Protocol 004), STPS (Protocol 004 X1), LTPS (Protocol 013)
Comparator
standard medical management of patients with zoster / PHN
Economic model
CUA
ICER note
Economic model presented but ICER values not stated in public text; likely commercially sensitive.
ICER (historical)
$15k/QALY–$45k/QALY in an earlier submission (2014) — the latest submission carried no numeric base case. No single PSD states this combined range; see source PSDs.

Submission history

Similar precedents

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