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IvermectinSoolantra

Recommended DermatologyAuthority RequiredLater-line line

Treatment of scabies when prior topical treatment has failed or is contra-indicated, and treatment of crusted scabies in conjunction with topical therapy.

1
Submissions
2014–14
On the record
ICER range
Not modelled
Cost basis

Decisions on record

3 decisions
  • Meeting Nov 2021 Recommended Scabies (sarcoptic/typical) no PSD
  • Meeting Mar 2014 Recommended Stromectol® Merck Sharp & Dohme (Australia) Pty Ltd Scabies To request Authority Required (STREAMLINED) General Schedule listing for the treatment of scabies where prior topical treatment has failed or is contra-indicated and for crusted scabies in conjunction with topical therapy. For the indicatio
  • Meeting Jul 2013 Recommended Round worm infestation no PSD

Access path

1 submission · public record
  1. TGA registered · Soolantra

    TGA label narrower than the PBS population

  2. Mar 2014
    Recommended · restricted

    vs placebo for crusted scabies; benzyl benzoate for typical…

  3. PBS listing · Authority Required
RecommendedDeferredNot recommended

Cost-effectiveness

Cost-consequence analysis presented; cost per cure calculated but not expressed as a traditional ICER ($/QALY or $/LY). Economic analysis focused on cost per cure rather than cost-effectiveness ratio.

Economic model disputed

Decision context

PopulationAdults and children (excluding those aged less than 5 years and/or weighing less than 15kg) with typical scabies after failure of both permethrin and benzyl benzoate, or with crusted scabies in conjunction with topical therapy.

Submission history

1 entries
DecidedOutcomeComparatorICEREvidence
Mar 2014 Recommended · restricted placebo for crusted scabies; benzyl benzoate for typical scabies after failure of topical treatment RCT · Clinical cure

Similar precedents

By decision profile

Regulatory · TGA

Label narrower than PBS population — PBAC restricts to age ≥5 years and weight ≥15kg; requires failure of both permethrin and benzyl benzoate for typical scabies.