script.reportAU
Oncology

Anastrozole

Brand: Arimidex

PBAC's latest decision on Anastrozole: Recommended with restriction (2005). Considered for Extension of restricted benefit listing to allow PBS-subsidised treatment of hormone-dependent early breast cancer in all post-menopausal women.

PBAC outcome
Recommended with restriction
Restricted
ICER (AUD/QALY)
$45k/QALY
Range: $15k/QALY–$45k/QALY
Submissions
1
first 2005
Submissions
1
2005 → 2005

Eligible population

Post-menopausal women with hormone-dependent early breast cancer.

Therapy area
Oncology
Line of therapy
First-line
Evidence base
RCT
Primary endpoint
DFS
Pivotal trial size
6,241 patients
Key trials
ATAC
Comparator
tamoxifen
Economic model
CUA
Budget impact
$20M
Eligible patients/year
30,000

Similar precedents

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