Disease index

multiple sclerosis

Neurology · 2006–2025

45decisions
20medicines
23carried consumer input
130individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
ocrelizumab Treatment of adult patients with relapsing-remitting multiple sclerosis (RRMS). Ocrelizumab SC provides an alternative subcutaneous administration route to the… Jul 2025 Recommended with restriction 14 individuals
ublituximab Treatment of adult patients with relapsing-remitting multiple sclerosis (RRMS) with active disease defined by clinical or imaging features. May 2025 Recommended with restriction 1 individuals
natalizumab Treatment of clinically definite relapsing-remitting multiple sclerosis (RRMS) to delay the progression of physical disability and reduce the frequency of… Mar 2025 Recommended with restriction none received
ofatumumab Treatment of relapsing remitting multiple sclerosis (RRMS) in adult patients with relapsing forms of multiple sclerosis to delay progression of physical… Mar 2024 Not recommended input received MS Australia
fingolimod, ofatumumab, siponimod Amendment to PBS listings to allow nurse practitioners to initiate and continue treatment of fingolimod, ofatumumab, and siponimod in consultation with a… Nov 2024 Recommended input received
natalizumab Treatment of clinically definite relapsing-remitting multiple sclerosis (RRMS) via subcutaneous injection (150 mg in 1 mL prefilled syringe formulation). Mar 2023 Recommended with restriction 8 individuals
cladribine Treatment of relapsing-remitting multiple sclerosis (RRMS) to reduce the frequency of clinical relapses and to delay the progression of physical disability. Nov 2023 Not recommended none received
natalizumab Treatment of clinically definite relapsing-remitting multiple sclerosis. Jul 2022 Recommended none received
diroximel fumarate Treatment of relapsing-remitting multiple sclerosis (RRMS) in patients diagnosed as clinically definite RRMS by MRI with at least two documented relapses… Mar 2022 Recommended with restriction 6 individuals MS Australia
glatiramer acetate Treatment of multiple sclerosis. The submission requested listing a new form of 40 mg glatiramer acetate pre-filled pen under the same circumstances as the… Mar 2022 Recommended 1 individuals MS Australia
glatiramer acetate Treatment of relapsing-remitting multiple sclerosis (RRMS), including reduction of relapse frequency and treatment of patients with a single clinical event… Mar 2021 Recommended none received
ofatumumab Treatment of relapsing-remitting multiple sclerosis (RRMS) in patients with clinically definite diagnosis confirmed by MRI of brain and/or spinal cord, who… Mar 2021 Recommended with restriction 4 individuals MS Australia
tetracosactide Treatment of hypsarrhythmia and/or infantile spasms, and acute exacerbations in patients with multiple sclerosis. Mar 2021 Deferred none received
cladribine Treatment of relapsing-remitting multiple sclerosis (RRMS) to reduce the frequency of clinical relapses and to delay the progression of physical disability. Nov 2021 Not recommended 1 individuals
ozanimod Treatment of clinically definite relapsing-remitting multiple sclerosis (RRMS) in adult patients. Sep 2020 Recommended with restriction input received MS Australia
siponimod Treatment of relapse-onset phenotypes of multiple sclerosis (RRMS and SPMS), including patients with EDSS 6.0/6.5. Jul 2020 Recommended with restriction 2 individuals
nabiximols Adjunctive treatment of moderate to severe spasticity in patients with multiple sclerosis who have not adequately responded to oral anti-spasticity agents. Mar 2020 Not recommended 4 individuals
fingolimod Treatment of relapsing-remitting multiple sclerosis (RRMS) in paediatric and adolescent patients weighing 40 kg or less. Jul 2019 Recommended with restriction input received
dimethyl fumarate Treatment of patients with relapsing-remitting multiple sclerosis (RRMS). Nov 2019 Recommended with restriction none received
cladribine Treatment of relapsing-remitting multiple sclerosis (RRMS) to reduce the frequency of clinical relapses and to delay the progression of physical disability. Jul 2018 Recommended with restriction 8 individuals
cladribine Treatment of relapsing remitting multiple sclerosis (RRMS) to reduce the frequency of clinical relapses and to delay the progression of physical disability. Mar 2018 Not recommended 26 individuals
glatiramer acetate Treatment of clinically isolated syndrome suggestive of multiple sclerosis in patients thought to be at high risk of subsequent diagnosis with clinically… Jul 2017 Not recommended input received
ocrelizumab Treatment of relapsing-remitting multiple sclerosis (RRMS) in adult patients. Ocrelizumab is positioned as a first-line alternative to fingolimod, natalizumab… Jul 2017 Recommended with restriction 10 individuals
cladribine Treatment of relapsing-remitting multiple sclerosis (RRMS) to reduce the frequency of clinical relapses and to delay the progression of physical disability. Nov 2017 Not recommended 5 individuals
daclizumab Treatment of relapsing-remitting multiple sclerosis (RRMS) in patients with clinically definite disease, at least 2 documented attacks in the preceding 2… Jul 2016 Deferred input received
dimethyl fumarate Treatment of patients with relapsing-remitting multiple sclerosis to reduce the frequency of relapses and to delay the progression of disability. Jul 2016 Recommended input received
teriflunomide Treatment of patients with relapsing-remitting multiple sclerosis (RRMS). Nov 2016 Not recommended none received
glatiramer acetate Initial and continuing treatment of clinically definite relapsing-remitting multiple sclerosis in ambulatory patients who have experienced at least two… Mar 2015 Recommended input received
alemtuzumab Treatment of relapsing-remitting multiple sclerosis with active disease defined by clinical or imaging features. Jul 2014 Recommended with restriction 40 individuals
fampridine Symptomatic improvement of walking ability in ambulatory patients with clinically definite multiple sclerosis who meet specified criteria (EDSS score 4-7,… Mar 2014 Not recommended unclear
alemtuzumab Treatment of relapsing-remitting multiple sclerosis (RRMS), as first-line therapy in patients with poor prognostic signs and as escalation therapy in… Nov 2014 Not recommended unclear
peginterferon beta-1a First-line treatment of patients with remitting-relapsing multiple sclerosis who have experienced at least 2 documented attacks of neurological dysfunction in… Nov 2014 Recommended with restriction input received
dimethyl fumarate Treatment of relapsing-remitting multiple sclerosis to reduce the frequency of relapses and to delay the progression of disability. Jul 2013 Recommended no section in document
nabiximols Treatment of moderate to severe spasticity due to multiple sclerosis in patients who are intolerant to anti-spasticity medication and/or have not adequately… Jul 2013 Not recommended unclear
teriflunomide Initial and continuing treatment of relapsing-remitting multiple sclerosis (RRMS) in ambulatory patients who have experienced at least 2 documented attacks of… Jul 2013 Recommended with restriction unclear
fampridine Symptomatic improvement of walking ability in ambulatory patients with clinically definite multiple sclerosis. Nov 2012 Not recommended unclear
teriflunomide Initial and continuing treatment of clinically definite relapsing-remitting multiple sclerosis in ambulatory patients who have experienced at least 2… Nov 2012 Not recommended unclear
fampridine Symptomatic improvement of walking ability for an ambulatory patient with clinically definite multiple sclerosis who meets certain criteria. 2012 Not recommended unclear
Teriflunomide Initial and continuing treatment of clinically definite relapsing-remitting multiple sclerosis in ambulatory patients who meet certain criteria. 2012 Recommended unclear
cladribine initial and continuing treatment of relapsing–remitting multiple sclerosis (RRMS) in an ambulatory patient who has experienced at least two documented attacks… Mar 2011 Not recommended no section in document
fingolimod Initial treatment of clinically definite relapsing-remitting multiple sclerosis in ambulatory (without assistance or support) patients who have experienced at… Mar 2011 Recommended unclear
Interferon beta-1b treatment of ambulatory patients with relapsing-remitting multiple sclerosis (MS) characterised by at least two attacks of neurologic dysfunction over a two… Mar 2007 Not recommended no section in document
interferon beta-1b Treatment of relapsing-remitting multiple sclerosis in ambulatory patients diagnosed using McDonald criteria, including those with a single clinical attack and… Mar 2007 Not recommended no section in document
natalizumab initial and continuing treatment of clinically definite relapsing-remitting multiple sclerosis in ambulatory patients eighteen years of age or older. Nov 2006 Not recommended no section in document
natalizumab Initial and continuing treatment of clinically definite relapsing-remitting multiple sclerosis in ambulatory patients eighteen years of age or older. Nov 2006 Recommended with restriction no section in document

Who spoke

MS Australia

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 23 of 32 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.