Disease index

growth hormone deficiency

Endocrinology · 2016–2023

10decisions
3medicines
4carried consumer input
94individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
somatropin Treatment of severe late onset growth hormone deficiency (GHD) in adults. Sep 2023 Recommended with restriction none received
somapacitan Treatment of paediatric patients with growth hormone deficiency (GHD), including short stature associated with biochemical GHD and short stature slow growth. Jul 2023 Recommended with restriction 4 individuals
somapacitan Treatment of adult growth hormone deficiency (AGHD) in patients aged 18 years and above, and those under 18 years of age with a mature skeleton. Mar 2022 Recommended with restriction 10 individuals Australian Pituitary Foundation
somatrogon Treatment of growth hormone deficiency (GHD) in paediatric patients, including short stature associated with biochemical growth hormone deficiency (SSABGHD)… Mar 2022 Recommended with restriction 12 individuals Australian Pituitary Foundation
somatropin Treatment of adults with severe growth hormone deficiency, specifically childhood-onset growth hormone deficiency due to congenital, genetic or structural… Aug 2019 Noted no section in document
somatropin Treatment of adults with severe growth hormone deficiency. The submission concerns the requirement for prescribers to use the Quality of Life in Adult Growth… Mar 2019 Recommended with restriction no section in document
somatropin Short stature and slow growth in children requiring growth hormone therapy. Jul 2018 Recommended with restriction none received
somatropin Treatment of adults with severe growth hormone deficiency (GHD) with substantially impaired quality of life at baseline. Jul 2017 Recommended with restriction none received
somatropin Growth hormone deficiency in children and adults, including short stature due to decreased or failed secretion of pituitary growth hormone, severe adult growth… Mar 2016 Recommended none received
somatropin Treatment of adults with severe growth hormone deficiency (GHD) and substantially impaired quality of life (QoL) at baseline. Nov 2016 Deferred 68 individuals Australian Pituitary Foundation · Endocrine Society of Australia · Pituitary Foundation

Who spoke

Australian Pituitary Foundation · Endocrine Society of Australia · Pituitary Foundation

What the PBS pays

$38M in government benefit over 2024–25, across 20,050 services.

This is spend on the medicines considered for this condition, not spend on the disease. A medicine used for several conditions is counted in full under each, so figures across conditions add to more than national PBS expenditure.

MedicineGovernment benefit
somatropin $28.9M
somatrogon $9.3M

Appraised elsewhere

NICE, in England and Wales, has appraised 2 technologies for this condition, recommending 2 . A different committee, a different population and a different price: this is what has been looked at there, not a verdict on what happened here.

TechnologyAppraisalOutcomeDate
somapacitanSomapacitan for treating growth hormone deficiency in people 3 to 17 years TA1066 recommended 2025-06
human growth hormoneHuman growth hormone (somatropin) in adults with growth hormone deficiency TA64 recommended restricted 2003-08

Registered, not subsidised

Medicines on the ARTG for this condition with no PBAC record at all. Registration and subsidy are separate decisions: a medicine can be legally available in Australia and never have been put to the committee.

MedicineOn the ARTG sinceRegistrations
lonapegsomatropinSKYTROFA lonapegsomatropin 11 mg powder and solvent for solution for i 2025 9

The ARTG export holds current registrations only, so the year is the earliest entry still on the register rather than a first-registration date. The condition here comes from the registered label, which is usually broader than the population a sponsor asks to have subsidised.

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 4 of 10 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.