Disease index

familial hypercholesterolaemia

Cardiovascular · 2016–2024

6decisions
2medicines
4carried consumer input
1individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
evolocumab Treatment of homozygous familial hypercholesterolaemia (HoFH), heterozygous familial hypercholesterolaemia (HeFH) and non-familial hypercholesterolaemia… Mar 2024 Recommended with restriction 1 individuals
inclisiran Amendment to restriction level (Authority Required Telephone/Online to Authority Required STREAMLINED) for initial and grandfathered listings for treatment of… Nov 2024 Recommended with restriction input received Heart Support Australia
evolocumab Treatment of homozygous familial hypercholesterolaemia (ho-FH), heterozygous familial hypercholesterolaemia (he-FH), and non-FH hypercholesterolaemia in… Mar 2021 Recommended none received
evolocumab Amendment to treatment criteria for evolocumab for familial hypercholesterolaemia (homozygous and heterozygous) and non-familial hypercholesterolaemia to allow… Nov 2020 Not recommended input received
evolocumab Treatment of patients with Familial Hypercholesterolaemia (FH) and either symptomatic atherosclerotic cardiovascular disease (ASCVD) or FH with very high… Mar 2018 Recommended with restriction none received
evolocumab Treatment of familial hypercholesterolaemia (homozygous familial hypercholesterolaemia recommended; heterozygous familial hypercholesterolaemia not… Mar 2016 Recommended with restriction input received Familial Hypercholesterolaemia Australasia Network · FH Family Support Group

Who spoke

Familial Hypercholesterolaemia Australasia Network · FH Family Support Group · Heart Support Australia

What the PBS pays

$101M in government benefit over 2024–25, across 197,739 services.

This is spend on the medicines considered for this condition, not spend on the disease. A medicine used for several conditions is counted in full under each, so figures across conditions add to more than national PBS expenditure.

MedicineGovernment benefit
evolocumab $63.2M
inclisiran $38.2M

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 4 of 6 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.