Disease index

Dravet syndrome

Neurology · 2020–2026

4decisions
3medicines
2carried consumer input
0individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
cannabidiol Severe myoclonic epilepsy in infancy (Dravet syndrome); adjunctive therapy to antiseizure medications. Mar 2026 Recommended with restriction unclear
fenfluramine Treatment of seizures associated with Dravet Syndrome in patients not adequately controlled despite treatment with at least 2 other antiepileptic drugs. Nov 2024 Recommended with restriction input received Epilepsy Action Australia · Epilepsy Society of Australia · Epilepsy Society
cannabidiol Adjunctive therapy to treat seizures associated with Lennox-Gastaut syndrome or Dravet syndrome in patients 2 years of age and older. Jul 2020 Deferred input received Epilepsy Society of Australia · Epilepsy Society · Epilepsy Foundation
stiripentol Adjunctive treatment of generalised tonic-clonic and clonic seizures associated with severe myoclonic epilepsy in infancy (SMEI, also known as Dravet syndrome)… Mar 2020 Recommended with restriction none received

Who spoke

Epilepsy Society of Australia · Epilepsy Society · Epilepsy Foundation · Epilepsy Action Australia

What the PBS pays

$19M in government benefit over 2024–25, across 7,545 services.

This is spend on the medicines considered for this condition, not spend on the disease. A medicine used for several conditions is counted in full under each, so figures across conditions add to more than national PBS expenditure.

MedicineGovernment benefit
cannabidiol $16.6M
stiripentol $1.2M
fenfluramine $0.6M

Appraised elsewhere

NICE, in England and Wales, has appraised 2 technologies for this condition, recommending 2 . A different committee, a different population and a different price: this is what has been looked at there, not a verdict on what happened here.

TechnologyAppraisalOutcomeDate
fenfluramineFenfluramine for treating seizures associated with Dravet syndrome TA808 recommended restricted 2022-07
cannabidiolCannabidiol with clobazam for treating seizures associated with Dravet syndrome TA614 recommended restricted 2019-12

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 2 of 4 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.