Disease index

chemotherapy-induced nausea and vomiting

Oncology · 2009–2023

15decisions
8medicines
4carried consumer input
1individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
fosnetupitant/palonosetron Prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly or moderately emetogenic cancer chemotherapy in… Mar 2023 Recommended with restriction input received
netupitant with palonosetron Prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly and moderately emetogenic cancer chemotherapy. Mar 2023 Recommended with restriction 1 individuals Society of Hospital Pharmacists of Australia
fosnetupitant with palonosetron Prevention of nausea and vomiting associated with cytotoxic chemotherapy in patients receiving moderately or highly emetogenic chemotherapy regimens. Jul 2020 Recommended with restriction none received
ondansetron Nausea and vomiting associated with radiotherapy or oral chemotherapy being used to treat malignancy. Mar 2020 Recommended with restriction no section in document
aprepitant Prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic and moderately emetogenic cancer… Jul 2019 Recommended with restriction no section in document
aprepitant Prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) associated with carboplatin or oxaliplatin-based regimens from the first… Mar 2016 Recommended with restriction none received
fosaprepitant Prevention of nausea and vomiting associated with cytotoxic chemotherapy, including highly emetogenic chemotherapy, breast cancer chemotherapy with… Nov 2016 Recommended with restriction none received
netupitant with palonosetron Prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) associated with moderately emetogenic chemotherapy (MEC), including secondary… Nov 2016 Recommended with restriction input received
netupitant/palonosetron Prevention of acute and delayed chemotherapy-induced nausea and vomiting in patients treated with highly emetogenic chemotherapy for malignancy, and in breast… Jul 2015 Recommended with restriction input received
netupitant/palonosetron Prevention of acute and delayed chemotherapy-induced nausea and vomiting associated with highly emetogenic chemotherapy, anthracycline plus cyclophosphamide… Mar 2015 Not recommended none received
aprepitant Prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) associated with carboplatin or oxaliplatin-based chemotherapy regimens. Nov 2015 Not recommended none received
aprepitant Management of nausea and vomiting associated with moderately emetogenic cytotoxic chemotherapy in patients who have had a prior episode of chemotherapy-induced… Mar 2010 Recommended with restriction no section in document
palonosetron hydrochloride Management of nausea and vomiting associated with cytotoxic chemotherapy being used to treat malignancy which occurs within 48 hours of chemotherapy… Mar 2010 Recommended with restriction no section in document
aprepitant Management of nausea and vomiting associated with moderately emetogenic cytotoxic chemotherapy in patients who have had a prior episode of chemotherapy-induced… Mar 2010 Recommended with restriction no section in document
aprepitant Prevention of chemotherapy-induced nausea and vomiting (CINV) associated with moderately emetogenic cancer chemotherapy. Nov 2009 Not recommended no section in document

Who spoke

Society of Hospital Pharmacists of Australia

What the PBS pays

$80M in government benefit over 2024–25, across 1,558,020 services.

This is spend on the medicines considered for this condition, not spend on the disease. A medicine used for several conditions is counted in full under each, so figures across conditions add to more than national PBS expenditure.

MedicineGovernment benefit
fosnetupitant with palonosetron $15M
fosnetupitant/palonosetron $15M
netupitant with palonosetron $15M
netupitant/palonosetron $15M
palonosetron hydrochloride $15M
ondansetron $5M
fosaprepitant $0.3M
aprepitant $0.1M

Registered, not subsidised

Medicines on the ARTG for this condition with no PBAC record at all. Registration and subsidy are separate decisions: a medicine can be legally available in Australia and never have been put to the committee.

MedicineOn the ARTG sinceRegistrations
granisetronAPO-GRANISETRON granisetron hydrochloride 1mg/1mL injection ampoule 1997 9

The ARTG export holds current registrations only, so the year is the earliest entry still on the register rather than a first-registration date. The condition here comes from the registered label, which is usually broader than the population a sponsor asks to have subsidised.

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 4 of 11 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.