Disease index

ALK+ NSCLC

Oncology · 2013–2026

8decisions
5medicines
6carried consumer input
649individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
alectinib Adjuvant therapy for anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) after tumour resection in patients with tumours ≥4 cm or… Mar 2026 Recommended with restriction no section in document
alectinib Adjuvant treatment in adult patients following tumour resection of anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) (tumours ≥4 cm… May 2025 Recommended with restriction 9 individuals Medical Oncology Group · Rare Cancers Australia · Lung Foundation Australia · ALK Positive Australia
brigatinib Locally advanced (Stage IIIB) or metastatic (Stage IV) anaplastic lymphoma kinase (ALK)-positive non-squamous or not otherwise specified non-small cell lung… Nov 2019 Recommended with restriction 70 individuals
lorlatinib Treatment of patients with metastatic (Stage IV) anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC), who have disease progression… Nov 2019 Recommended with restriction 118 individuals
alectinib Treatment of patients with locally advanced (Stage IIIB) or metastatic (Stage IV) ALK-positive non-small cell lung cancer (NSCLC) who have disease progression… Jul 2017 Recommended with restriction 173 individuals
ceritinib Treatment of adult patients with anaplastic lymphoma kinase (ALK) positive locally advanced or metastatic non-small cell lung cancer (NSCLC) who have… Nov 2016 Recommended with restriction 18 individuals Rare Cancers Australia · Lung Foundation · Medical Oncology Group
crizotinib Treatment of patients with anaplastic lymphoma kinase (ALK)-positive locally advanced or metastatic non-small cell lung cancer (NSCLC) following disease… Nov 2014 Recommended with restriction 261 individuals
crizotinib Second-line treatment of patients with anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC) who have disease progression… Nov 2013 Recommended with restriction no section in document

Who spoke

Medical Oncology Group · Rare Cancers Australia · Lung Foundation Australia · ALK Positive Australia · Lung Foundation

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 6 of 7 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.