PBAC's latest decision on Zonisamide: Recommended with restriction (2007). Considered for Treatment of partial epileptic seizures, which are not controlled satisfactorily by other anti-epileptic drugs.
PBAC outcome
Recommended with restriction
Authority Required (STREAMLINED)
ICER (AUD/QALY)
Cost-min
cost-minimisation analysis
Submissions
1
first 2007
Submissions
1
2007 → 2007
Eligible population
adult patients with partial seizures, with or without secondary generalisation
Therapy area
Neurology
Line of therapy
Later-line
Evidence base
RCT | Meta-analysis
Primary endpoint
Other
Key trials
302, 922, 912-EUR, 912-US
Comparator
lamotrigine
Economic model
Cost-minimisation
Budget impact
$10M
ICER note
Cost-minimisation analysis used; no ICER calculated