Rotavirus Vaccine, Live, Oral, Pentavalent
Recommended VaccinesUnrestrictedNot applicable line
Prevention of rotavirus gastroenteritis in infants vaccinated at 2, 4 and 6 months of age.
2
Submissions
1 resub
2006–06
On the record
$45k–75k
ICER range
2 sourced ICERs · 2006
ICER stated
Cost basis
Access path
- Jul 2006Not recommended
uncertain cost-effectiveness at the price requested, debatable QALY gain extrapolation from temporary self-limiting…
- ↻ resubmittedNov 2006Recommended
ICER dropped $75,000 → $15,000 (-80%)
- PBS listing · Unrestricted
RecommendedDeferredNot recommended
Cost-effectiveness
The document states the cost per QALY gained was '<$15,000' in the revised evaluation, but does not provide an upper bound or precise range.
The cost (excluding work loss costs) per QALY gained in the revised evaluation was <$15,000, compared to $45,000 – $75,000 in the original submission. PSD · 2006
Decision context
PopulationInfants at 2, 4 and 6 months of age to prevent rotavirus gastroenteritis.
Submission history
| Decided | Outcome | Comparator | ICER | Evidence |
|---|---|---|---|---|
| Nov 2006 | Recommended | standard medical management without rotavirus vaccination | $15k | Meta-analysis |
| Jul 2006 | Not recommended | standard medical management without rotavirus vaccination | $45k–75k | RCT |