script.reportAU
Cardiovascular

Rivaroxaban

Brand: Xarelto

PBAC's latest decision on Rivaroxaban: Noted (2024). Considered for New pack sizes (2.5 mg 98-pack and 10 mg 14-pack) for existing indications: chronic stable atherosclerotic disease (chronic coronary artery disease and/or peripheral artery disease) for the 2.5 mg strength, and prevention of venous thromboembolism in total hip or knee replacement for the 10 mg strength.

PBAC outcome
Noted
Authority Required
ICER (AUD/QALY)
Cost-min
cost-minimisation analysis
Submissions
10
first 2009
Submissions
10
2009 → 2024

Eligible population

Patients with chronic stable atherosclerotic disease (chronic coronary artery disease and/or peripheral artery disease) for the 2.5 mg strength; patients undergoing total hip or knee replacement for the 10 mg strength.

Therapy area
Cardiovascular
Line of therapy
Not applicable
Evidence base
Cost-minimisation
Primary endpoint
Cost-minimisation
Comparator
existing pack sizes (Xarelto 2.5 mg 60-pack and Xarelto 10 mg 15-pack)
Economic model
Cost-minimisation
ICER note
Cost-minimisation analysis only; no ICER calculated. Submission based on cost-per-tablet comparison of new pack sizes to existing pack sizes.
ICER (historical)
$15k/QALY–$45k/QALY across 5 submissions (2009–2020) — the latest submission carried no numeric base case. No single PSD states this combined range; see source PSDs.

Submission history

Similar precedents

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