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Gastroenterology

Peginterferon alfa-2b

PBAC's latest decision on Peginterferon alfa-2b: Recommended with restriction (2005). Considered for treatment of chronic hepatitis C in patients who have not previously received interferon treatment, with or without ribavirin.

PBAC outcome
Recommended with restriction
2005
ICER (AUD/QALY)
$45k/QALY
Range: $15k/QALY–$45k/QALY
Submissions
1
first 2005
Submissions
1
2005 → 2005

Eligible population

patients with no or mild hepatitis C

Therapy area
Gastroenterology
Line of therapy
First-line
Evidence base
RCT
Primary endpoint
SVR
Key trials
C/I98-580, Mangia (2004), Verbaan (2002), Wright (2005a)
Comparator
Pegatron therapy in patients with stage F1/A2-A3, F2, F3 and F4 fibrosis
Economic model
CUA
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