treatment-resistant depression
Mental health · 2021–2024
Every decision
| Medicine | Meeting | Outcome | Consumer input |
|---|---|---|---|
| esketamine Treatment of treatment-resistant depression (TRD) in adults with major depressive disorder who have not responded adequately to at least two separate courses… | Dec 2024 | Deferred | 2 individuals |
| esketamine Treatment of adult patients with treatment-resistant depression (major depressive disorder who have not responded adequately to at least 2 separate courses of… | Jul 2023 | Not recommended | 58 individuals |
| esketamine Treatment-resistant depression (TRD) in adult patients with major depressive disorder who have not responded adequately to at least two separate courses of… | Jul 2022 | Not recommended | 22 individuals Lived Experience Australia · Samy Medical Group |
| esketamine Treatment of treatment-resistant depression (TRD) in adults who have not responded adequately to at least two different antidepressants of adequate dose and… | Jul 2021 | Not recommended | 2 individuals |
Who spoke
Lived Experience Australia · Samy Medical Group
What the PBS pays
$3M in government benefit over 2024–25, across 630 services.
This is spend on the medicines considered for this condition, not spend on the disease. A medicine used for several conditions is counted in full under each, so figures across conditions add to more than national PBS expenditure.
| Medicine | Government benefit |
|---|---|
| esketamine | $2.6M |
Appraised elsewhere
NICE, in England and Wales, has appraised 1 technology for this condition, recommending 0 . A different committee, a different population and a different price: this is what has been looked at there, not a verdict on what happened here.
| Technology | Appraisal | Outcome | Date |
|---|---|---|---|
| esketamine nasal sprayEsketamine nasal spray for treatment-resistant depression | TA854 | unknown | 2022-12 |
Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 4 of 4 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.