Disease index

pulmonary arterial hypertension

Cardiovascular · 2005–2025

17decisions
12medicines
7carried consumer input
385individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
sotatercept Add-on therapy for adult patients with Group 1 pulmonary arterial hypertension (PAH) WHO Functional Class II (with elevated NT-proBNP) or III who have been on… Mar 2025 Not recommended 227 individuals Lung Foundation Australia · Australian Scleroderma Interest Group
tadalafil Treatment of pulmonary arterial hypertension (PAH), specifically a new 60-tablet pack size to align treatment supply duration with combination endothelin… Mar 2024 Recommended input received Pulmonary Hypertension Society · Lung Foundation Australia
macitentan with tadalafil Continuing treatment of pulmonary arterial hypertension (PAH) in patients who are on stable doses of macitentan and tadalafil as combination therapy. Nov 2024 Recommended with restriction input received Lung Foundation Australia
selexipag Triple agent sequential add-on therapy with an endothelin receptor antagonist (ERA) and a phosphodiesterase-5 inhibitor (PDE-5i) for patients with World Health… Jul 2020 Recommended with restriction 113 individuals Pulmonary Hypertension Network Australia · Lung Foundation Australia · PAH Association
selexipag Treatment of pulmonary arterial hypertension (PAH) as triple therapy (in combination with an ERA and a PDE-5 inhibitor), or as dual therapy for patients… Mar 2017 Not recommended 33 individuals
selexipag Treatment of pulmonary arterial hypertension (PAH) as add-on therapy in patients stabilised on background therapy with an endothelin receptor antagonist (ERA)… Mar 2016 Not recommended 3 individuals
epoprostenol Long-term treatment via continuous intravenous infusion of pulmonary arterial hypertension (idiopathic, familial, or associated with scleroderma spectrum of… Nov 2016 Recommended none received
Pulmonary arterial hypertension (PAH) Jul 2015 Recommended 9 individuals
epoprostenol Long-term treatment via continuous intravenous infusion of pulmonary arterial hypertension, including idiopathic, familial, and PAH associated with scleroderma… Jul 2014 Recommended no section in document
macitentan Idiopathic pulmonary arterial hypertension (IPAH), PAH secondary to connective tissue disease (PAH-CTD), and PAH associated with congenital heart disease… Mar 2014 Recommended with restriction unclear
riociguat Treatment of primary pulmonary hypertension, pulmonary arterial hypertension (PAH) secondary to connective tissue disease, and PAH associated with congenital… Mar 2014 Recommended with restriction unclear
tadalafil Treatment of WHO functional class III primary pulmonary arterial hypertension (PAH) and WHO functional class III PAH secondary to connective tissue disease in… Nov 2011 Recommended with restriction no section in document
epoprostenol sodium Treatment of pulmonary arterial hypertension (PAH) secondary to scleroderma spectrum of diseases: second-line therapy for WHO functional class III patients who… Nov 2011 Recommended with restriction no section in document
ambrisentan treatment of primary pulmonary hypertension (PPH) or pulmonary arterial hypertension secondary to connective tissue disease (PAH-CTD) in patients with WHO… Jul 2009 Recommended with restriction no section in document
bosentan monohydrate Pulmonary arterial hypertension associated with congenital systemic to pulmonary shunts including Eisenmenger's physiology in patients with WHO functional… Mar 2008 Recommended with restriction no section in document
treprostinil sodium treatment of primary pulmonary arterial hypertension or pulmonary arterial hypertension associated with connective tissue disease, in patients with disease of… Nov 2005 Recommended no section in document
treprostinil sodium Treatment of primary pulmonary arterial hypertension or pulmonary arterial hypertension associated with connective tissue disease, in patients with disease of… Nov 2005 Recommended no section in document

Who spoke

Lung Foundation Australia · Pulmonary Hypertension Network Australia · PAH Association · Australian Scleroderma Interest Group · Pulmonary Hypertension Society

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 7 of 11 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.