Disease index

primary progressive multiple sclerosis

Neurology · 2017–2020

2decisions
1medicine
2carried consumer input
72individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
ocrelizumab Treatment of early, active primary progressive multiple sclerosis (PPMS) diagnosed within the previous 5 years with evidence of active inflammatory disease in… Jul 2020 Not recommended 9 individuals MS Australia · MS Research Australia
ocrelizumab Treatment of primary progressive multiple sclerosis (PPMS) to delay the progression of physical disability. Nov 2017 Not recommended 63 individuals MS Australia · MS Research Australia

Who spoke

MS Australia · MS Research Australia

What the PBS pays

$249M in government benefit over 2024–25, across 15,188 services.

This is spend on the medicines considered for this condition, not spend on the disease. A medicine used for several conditions is counted in full under each, so figures across conditions add to more than national PBS expenditure.

MedicineGovernment benefit
ocrelizumab $248.8M

Appraised elsewhere

NICE, in England and Wales, has appraised 1 technology for this condition, recommending 1 . A different committee, a different population and a different price: this is what has been looked at there, not a verdict on what happened here.

TechnologyAppraisalOutcomeDate
ocrelizumabOcrelizumab for treating primary progressive multiple sclerosis TA585 recommended restricted 2019-06

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 2 of 2 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.