Disease index

opioid dependence

Pain · 2005–2023

8decisions
6medicines
2carried consumer input
0individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
buprenorphine; buprenorphine with naloxone; methadone Treatment of opioid dependence within a framework of medical, social and psychological treatment. Mar 2023 Recommended with restriction no section in document
buprenorphine with naloxone Treatment of opioid dependence within a framework of medical, social and psychological treatment. Mar 2020 Not recommended input received
buprenorphine Maintenance treatment of opioid dependence within a framework of medical, social, and psychological treatment. Mar 2019 Recommended with restriction unclear
buprenorphine/naloxone Treatment of patients with opioid dependence within a framework of medical, social and psychological treatment. Nov 2019 Not recommended none received
buprenorphine Treatment of opioid dependence in adults and adolescents aged 16 years and over, administered as a prolonged-release once weekly or once monthly subcutaneous… Nov 2018 Not recommended input received
buprenorphine + naloxone Treatment of opiate dependence within a framework of medical, social and psychological treatment. Nov 2014 Recommended none received
buprenorphine hydrochloride with naloxone hydrochloride Treatment of opiate dependence, within a framework of medical, social and psychological treatment. Nov 2005 Recommended with restriction no section in document
buprenorphine hydrochloride with naloxone hydrochloride Treatment of opiate dependence within a framework of medical, social and psychological treatment. Nov 2005 Recommended with restriction no section in document

What the PBS pays

$1,414M in government benefit over 2024–25, across 19,546,209 services.

This is spend on the medicines considered for this condition, not spend on the disease. A medicine used for several conditions is counted in full under each, so figures across conditions add to more than national PBS expenditure.

MedicineGovernment benefit
buprenorphine, buprenorphine with naloxone, methadone $254M
buprenorphine + naloxone $244.4M
buprenorphine hydrochloride with naloxone hydrochloride $244.4M
buprenorphine with naloxone $244.4M
buprenorphine/naloxone $244.4M
buprenorphine $182.7M

Appraised elsewhere

NICE, in England and Wales, has appraised 2 technologies for this condition, recommending 2 . A different committee, a different population and a different price: this is what has been looked at there, not a verdict on what happened here.

TechnologyAppraisalOutcomeDate
methadone and buprenorphineMethadone and buprenorphine for the management of opioid dependence TA114 recommended 2007-01
naltrexoneNaltrexone for the management of opioid dependence TA115 recommended restricted 2007-01

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 2 of 6 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.