Disease index

myelofibrosis

Haematology · 2013–2025

7decisions
3medicines
3carried consumer input
26individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
fedratinib Treatment of intermediate-2 and high-risk myelofibrosis (primary, post-polycythaemia vera, or post-essential thrombocythaemia) in patients who have had prior… May 2025 Not recommended 8 individuals
fedratinib Treatment of patients with intermediate-2/high-risk primary myelofibrosis, post-polycythaemia vera myelofibrosis, or post-essential thrombocythaemia… Nov 2025 Recommended no section in document
momelotinib Treatment of intermediate or high-risk primary myelofibrosis, post-polycythaemia vera myelofibrosis or post-essential thrombocythaemia myelofibrosis in… Nov 2024 Recommended with restriction 16 individuals
ruxolitinib First-line or second-line management of myelofibrosis (primary myelofibrosis, post-polycythemia vera myelofibrosis, or post-essential thrombocythemia… Jul 2016 Recommended none received
ruxolitinib First-line or second-line management of myelofibrosis in patients satisfying certain clinical criteria, including intermediate-2, high-risk, and intermediate-1… Mar 2015 Recommended none received
ruxolitinib Second-line treatment of myelofibrosis in patients with intermediate-2 or high-risk disease (according to IPSS) who are resistant, refractory, intolerant, or… Jul 2014 Deferred 2 individuals
ruxolitinib Treatment of disease-related symptoms in patients with intermediate or high-risk primary (idiopathic) myelofibrosis, post-polycythemia vera myelofibrosis or… Jul 2013 Not recommended unclear

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 3 of 6 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.