Disease index

late-onset Pompe disease

Rare disease · 2009–2025

7decisions
2medicines
2carried consumer input
16individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
cipaglucosidase alfa with miglustat Treatment of adults with late-onset Pompe disease (LOPD), a rare autosomal recessive glycogen storage disorder caused by GAA gene mutations leading to… Mar 2025 Not recommended 16 individuals
alglucosidase alfa Treatment of late-onset Pompe disease in patients with confirmed diagnosis based on enzymology or mutational analysis and clinical features of juvenile or… Mar 2013 Recommended unclear
alglucosidase alfa treatment of late-onset Pompe disease Nov 2012 Recommended no section in document
alglucosidase alfa Late-onset Pompe disease (acid alfa-glucosidase deficiency). Treatment aims to slow progressive muscle weakness and extend survival in patients with this rare… Nov 2012 Recommended no section in document
alglucosidase alfa treatment of late onset Pompe disease with a documented deficiency of acid alpha-glucosidase enzyme activity in muscle tissues, confirmed by laboratory tests… Nov 2010 Not recommended input received
alglucosidase alfa treatment of late-onset Pompe disease with a documented deficiency of acid alpha-glucosidase enzyme activity Mar 2009 Not recommended no section in document
alglucosidase alfa Treatment of late-onset Pompe disease (acid alfa-glucosidase deficiency) in patients with significant deterioration in lung function (FVC <80% predicted) or… Nov 2009 Recommended no section in document

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 1 of 1 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.