Disease index

idiopathic pulmonary fibrosis

Respiratory · 2015–2024

8decisions
2medicines
7carried consumer input
185individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
nintedanib Idiopathic Pulmonary Fibrosis (IPF) and Chronic Fibrosing Interstitial Lung Disease with a progressive phenotype (PF-ILD). Nov 2024 Noted input received
pirfenidone Treatment of idiopathic pulmonary fibrosis (IPF). This submission concerned new tablet formulations (267 mg and 801 mg) as alternatives to the previously… Mar 2018 Recommended with restriction none received
pirfenidone Idiopathic pulmonary fibrosis (IPF) in patients with confirmed diagnosis, FVC ≥50% predicted, and DLCO ≥30% predicted. Mar 2016 Recommended with restriction 1 individuals
nintedanib Treatment of patients with idiopathic pulmonary fibrosis (IPF), specifically mild to moderate IPF in patients meeting pulmonary function criteria. Nov 2016 Recommended with restriction 33 individuals Lung Foundation Australia
pirfenidone Treatment of idiopathic pulmonary fibrosis (IPF) in adults with confirmed diagnosis, FVC ≥50% predicted, and DLCO ≥30% predicted. Nov 2016 Deferred 50 individuals Lung Foundation Australia
nintedanib Treatment of idiopathic pulmonary fibrosis (IPF), a non-neoplastic irreversible fatal lung disease resulting from abnormal remodelling of lung tissue leading… Mar 2015 Not recommended 3 individuals
nintedanib Treatment of mild to moderate idiopathic pulmonary fibrosis (IPF) in patients aged 40 years or older with confirmed diagnosis and specific lung function… Nov 2015 Deferred 50 individuals Lung Foundation Australia · Lung Foundation
pirfenidone Treatment of idiopathic pulmonary fibrosis (IPF). Patients aged 40 years or older with confirmed IPF diagnosis, FVC ≥50% predicted, and DL_CO ≥30% predicted. Nov 2015 Not recommended 48 individuals Lung Foundation Australia · Lung Foundation

Who spoke

Lung Foundation Australia · Lung Foundation

What the PBS pays

$95M in government benefit over 2024–25, across 46,078 services.

This is spend on the medicines considered for this condition, not spend on the disease. A medicine used for several conditions is counted in full under each, so figures across conditions add to more than national PBS expenditure.

MedicineGovernment benefit
nintedanib $87M
pirfenidone $7.8M

Appraised elsewhere

NICE, in England and Wales, has appraised 3 technologies for this condition, recommending 3 . A different committee, a different population and a different price: this is what has been looked at there, not a verdict on what happened here.

TechnologyAppraisalOutcomeDate
nintedanibNintedanib for treating idiopathic pulmonary fibrosis when forced vital capacity is above 80% predicted TA864 recommended restricted 2023-02
pirfenidonePirfenidone for treating idiopathic pulmonary fibrosis TA504 recommended restricted 2018-02
nintedanibNintedanib for treating idiopathic pulmonary fibrosis TA379 recommended restricted 2016-01

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 7 of 8 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.