Disease index

hypophosphatasia

Metabolic · 2017–2018

2decisions
1medicine
2carried consumer input
61individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
asfotase alfa rch Treatment of patients with juvenile-onset hypophosphatasia (HPP; onset between 6 months and 17 years). Mar 2018 Not recommended 55 individuals Soft Bones Australia
asfotase alfa rch Treatment of patients with paediatric-onset hypophosphatasia (HPP), a rare metabolic disease presenting with defective bone mineralisation and associated… Jul 2017 Not recommended 6 individuals Soft Bones Australia

Who spoke

Soft Bones Australia

Registered, not subsidised

Medicines on the ARTG for this condition with no PBAC record at all. Registration and subsidy are separate decisions: a medicine can be legally available in Australia and never have been put to the committee.

MedicineOn the ARTG sinceRegistrations
asfotase alfaSTRENSIQ asfotase alfa rch 12 mg/0.30 ml solution for injection vial 2016 5

The ARTG export holds current registrations only, so the year is the earliest entry still on the register rather than a first-registration date. The condition here comes from the registered label, which is usually broader than the population a sponsor asks to have subsidised.

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 2 of 2 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.