Disease index

differentiated thyroid cancer

Oncology · 2015–2018

2decisions
2medicines
1carried consumer input
2individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
lenvatinib Locally advanced or metastatic differentiated thyroid cancer that is refractory to radioactive iodine, in patients for whom surgery is inappropriate and… Jul 2018 Recommended with restriction none received
sorafenib Treatment of locally advanced or metastatic, radioactive iodine refractory differentiated thyroid cancer (RAI-R DTC). Mar 2015 Deferred 2 individuals Rare Cancer Australia

Who spoke

Rare Cancer Australia

What the PBS pays

$32M in government benefit over 2024–25, across 8,313 services.

This is spend on the medicines considered for this condition, not spend on the disease. A medicine used for several conditions is counted in full under each, so figures across conditions add to more than national PBS expenditure.

MedicineGovernment benefit
lenvatinib $31.4M
sorafenib $0.7M

Appraised elsewhere

NICE, in England and Wales, has appraised 2 technologies for this condition, recommending 1 and declining 1. A different committee, a different population and a different price: this is what has been looked at there, not a verdict on what happened here.

TechnologyAppraisalOutcomeDate
cabozantinibCabozantinib for previously treated advanced differentiated thyroid cancer unsuitable for or refractory to radioactive iodine TA928 not recommended 2023-11
lenvatinib and sorafenibLenvatinib and sorafenib for treating differentiated thyroid cancer after radioactive iodine TA535 recommended restricted 2018-08

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 1 of 2 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.