Disease index

Crohn's disease

Gastroenterology · 2007–2026

44decisions
10medicines
29carried consumer input
233individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
upadacitinib Complex refractory fistulising Crohn's disease with externally draining enterocutaneous or rectovaginal fistula. Mar 2026 Recommended with restriction no section in document
adalimumab Treatment of immune-mediated inflammatory diseases (IMIDs) in paediatric patients under 18 years of age, with disease severity considered sufficient to cause… Jul 2025 Recommended with restriction 6 individuals
guselkumab Treatment of adults with severe Crohn's disease who have had an inadequate response, lost response, or were intolerant to either conventional therapy or a… Jul 2025 Recommended with restriction 1 individuals Colitis Australia
infliximab Multiple indications including rheumatoid arthritis, psoriatic arthritis, Crohn's disease in adults and children (6 to 17 years), refractory Crohn's disease,… Jul 2025 Recommended with restriction input received Colitis Australia
infliximab Biosimilar to Remicade for rheumatoid arthritis, psoriatic arthritis, Crohn's disease (adults and children 6-17 years), refractory Crohn's disease, ankylosing… Mar 2025 Recommended with restriction input received
infliximab Amendment to restriction level for continuing treatment of severe active rheumatoid arthritis, severe Crohn disease, severe chronic plaque psoriasis, severe… Mar 2025 Recommended with restriction input received
ustekinumab Severe chronic plaque psoriasis, severe psoriatic arthritis, severe Crohn disease, complex refractory fistulising Crohn disease, and moderate to severe… Mar 2025 Recommended with restriction input received
vedolizumab Dose escalation from 8-weekly to 4-weekly intravenous maintenance treatment in adults with moderate to severe ulcerative colitis or severe Crohn disease who… Nov 2025 Not recommended input received Colitis Australia
budesonide Treatment of mild to moderately active Crohn disease affecting the ileum and/or the ascending colon. Mar 2024 Recommended input received Colitis Australia
ustekinumab Treatment of paediatric severe chronic plaque psoriasis, severe Crohn disease, moderate to severe ulcerative colitis, and complex refractory fistulising Crohn… Mar 2024 Recommended input received Colitis Australia
vedolizumab Additional induction dose (week 10) for severe Crohn disease in patients who have not responded to the standard three-dose induction therapy (weeks 0, 2, 6). Mar 2024 Recommended input received Colitis Australia
ustekinumab Severe chronic plaque psoriasis (adult and paediatric), severe psoriatic arthritis, severe Crohn disease, and complex refractory fistulising Crohn disease. Nov 2024 Recommended input received Colitis Australia
upadacitinib Treatment of severe Crohn disease in adults who have failed to achieve an adequate response, or are contraindicated, to prior systemic therapy. Jul 2023 Recommended with restriction input received Colitis Australia
ustekinumab Complex refractory fistulising Crohn disease in adult patients. Jul 2023 Recommended with restriction input received Colitis Australia
risankizumab Severe Crohn's disease in adults who have failed to achieve an adequate response or are contraindicated to prior systemic therapy; Complex refractory… Jul 2022 Recommended with restriction input received Colitis Australia
ustekinumab Treatment of patients with Crohn disease and severe chronic plaque psoriasis requiring a 90 mg dose of ustekinumab, in a pre-filled syringe formulation. Jul 2022 Recommended none received
infliximab Treatment of ankylosing spondylitis, severe chronic plaque psoriasis, severe active psoriatic arthritis, and complex refractory fistulising Crohn's disease via… Mar 2022 Recommended with restriction unclear
adalimumab Rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, hidradenitis suppurativa, chronic plaque psoriasis, ulcerative colitis, Crohn's disease, and… Nov 2022 Not recommended 1 individuals
mesalazine Management of an acute episode of mild to moderate ulcerative proctitis (suppository); ulcerative colitis and Crohn disease (modified release granules). Mar 2020 Recommended 1 individuals
protein formula with carbohydrate, fat, vitamins, minerals and transforming growth factor beta-2 Dietary management of Crohn disease in the active or remission phases in adults and children over the age of 5 years, as enteral nutrition. Mar 2020 Not recommended input received Colitis Australia · Israel Medical Association
infliximab Treatment of adults with severe active rheumatoid arthritis, ankylosing spondylitis, severe refractory Crohn's disease, complex refractory fistulising Crohn's… Nov 2020 Recommended with restriction input received Colitis Australia · Parallel- Group
vedolizumab Maintenance treatment for patients with moderate to severe ulcerative colitis (MSUC) and severe Crohn's disease (CD) who have responded to intravenous… Nov 2020 Recommended with restriction input received Colitis Australia
budesonide Treatment of mild to moderate Crohn's disease affecting the ileum and/or the ascending colon. Mar 2019 Recommended 1 individuals
budesonide Treatment of patients with mild to moderate Crohn's disease affecting the ileum and/or ascending colon. Mar 2019 Recommended with restriction 2 individuals
infliximab Subsequent continuing treatment for severe Crohn disease, complex refractory fistulising Crohn disease, moderate to severe Crohn disease, moderate to severe… Mar 2019 Recommended with restriction 3 individuals
adalimumab Severe active rheumatoid arthritis, severe psoriatic arthritis, ankylosing spondylitis, severe chronic plaque psoriasis, juvenile idiopathic arthritis, severe… Jul 2018 Recommended 1 individuals
adalimumab Multiple indications including severe Crohn's disease, moderate to severe ulcerative colitis, severe active juvenile idiopathic arthritis, fistulising Crohn's… Jul 2018 Recommended with restriction none received
budesonide Treatment of mild to moderate Crohn's disease affecting the ileum and/or the ascending colon. Jul 2018 Recommended input received
mesalazine Treatment of ulcerative colitis and Crohn disease in patients with documented hypersensitivity reaction to sulphonamides or intolerance to sulfasalazine. Jul 2018 Recommended with restriction none received
ustekinumab Severe Crohn's disease and complex refractory fistulising Crohn's disease in adults aged 18 years or older who have failed conventional therapies. Mar 2017 Recommended 41 individuals
infliximab Change to initial and continuing treatment restrictions for the biosimilar brand of infliximab (Renflexis) for severe active rheumatoid arthritis, ankylosing… Nov 2017 Recommended with restriction none received
budesonide Treatment of mild to moderate Crohn's disease affecting the ileum and/or the ascending colon. Nov 2017 Not recommended 46 individuals
infliximab Biosimilar to Remicade for multiple indications including rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis, ulcerative colitis, and… Nov 2016 Recommended none received
infliximab Biosimilar to Remicade for rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis, ulcerative colitis, and Crohn's disease. Jul 2015 Recommended with restriction 2 individuals
vedolizumab Treatment of moderate to severe Crohn's disease in patients who have had an inadequate response with, lost response to, or are intolerant to either… Mar 2015 Recommended with restriction 98 individuals
adalimumab Treatment of severe refractory Crohn's disease in paediatric patients aged 6 to 17 years. Nov 2014 Recommended with restriction 30 individuals
infliximab complex refractory fistulising Crohn disease with a draining enterocutaneous or rectovaginal fistula Mar 2010 Recommended with restriction no section in document
infliximab Complex fistulising Crohn disease with a draining enterocutaneous or rectovaginal fistula. Mar 2010 Recommended with restriction no section in document
adalimumab treatment of complex refractory fistulising Crohn disease with a draining enterocutaneous or rectovaginal fistula Nov 2010 Recommended with restriction unclear
Infliximab treatment of refractory moderate to severe Crohn’s disease in paediatric patients (aged 6-17 years inclusive) Jul 2007 Recommended with restriction no section in document
infliximab Treatment of moderate to severe Crohn's disease in paediatric patients aged 6-17 years who are refractory to conventional therapies. Jul 2007 Recommended with restriction no section in document
Infliximab Treatment of severe Crohn’s disease in adults who have an inadequate response to conventional therapies, and for patients with an ileostomy or colectomy due to… Mar 2007 Recommended with restriction no section in document
adalimumab Treatment of patients with moderate to severe Crohn disease (CDAI > 300) or patients with an ileostomy or colectomy due to Crohn disease who have inadequate… Nov 2007 Recommended with restriction no section in document
adalimumab Treatment of patients with moderate to severe Crohn disease (CDAI > 300) or in patients with an ileostomy or colectomy due to Crohn disease. Nov 2007 Recommended with restriction no section in document

Who spoke

Colitis Australia · Parallel- Group · Israel Medical Association

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 29 of 36 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.