Disease index

classical Hodgkin's lymphoma

Haematology · 2017–2024

3decisions
2medicines
2carried consumer input
125individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
brentuximab vedotin First-line treatment of advanced (Stage III or IV) classical CD30+ Hodgkin lymphoma in combination with doxorubicin, vinblastine and dacarbazine (A+AVD). Mar 2024 Not recommended input received Leukaemia Foundation
pembrolizumab Treatment of relapsed or refractory classical Hodgkin's Lymphoma (rrcHL) in patients who have undergone autologous stem cell transplant or are not suitable for… Aug 2017 Recommended with restriction no section in document
pembrolizumab Treatment of relapsed or refractory classical Hodgkin's lymphoma (rrcHL) in patients who have progressed following autologous stem cell transplant (ASCT), or… Jul 2017 Deferred 125 individuals

Who spoke

Leukaemia Foundation

What the PBS pays

$761M in government benefit over 2024–25, across 88,651 services.

This is spend on the medicines considered for this condition, not spend on the disease. A medicine used for several conditions is counted in full under each, so figures across conditions add to more than national PBS expenditure.

MedicineGovernment benefit
pembrolizumab $739.6M
brentuximab vedotin $21.4M

Appraised elsewhere

NICE, in England and Wales, has appraised 2 technologies for this condition, recommending 1 and declining 1. A different committee, a different population and a different price: this is what has been looked at there, not a verdict on what happened here.

TechnologyAppraisalOutcomeDate
pembrolizumabPembrolizumab for treating relapsed or refractory classical Hodgkin lymphoma in people 3 years and over TA967 recommended restricted 2024-05
pembrolizumabPembrolizumab for treating relapsed or refractory classical Hodgkin lymphoma after stem cell transplant or at least 2 previous therapies TA772 not recommended 2022-02

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 2 of 3 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.