Disease index

bipolar I disorder

Mental health · 2008–2018

7decisions
5medicines
0carried consumer input
0individual submissions

No submission for this condition has carried consumer input, including the 2 made since the comments facility came into use.

Every decision

MedicineMeetingOutcomeConsumer input
aripiprazole Acute and maintenance treatment of schizophrenia in adults; maintenance treatment to prevent recurrence of manic or mixed episodes of bipolar I disorder in… Jul 2018 Recommended with restriction none received
quetiapine Maintenance therapy for treatment of acute mania, bipolar I disorder, and schizophrenia. The submission requested change in listing to allow up to 5 repeats… Mar 2018 Recommended no section in document
asenapine Treatment of acute mania or mixed episodes associated with bipolar I disorder (as monotherapy or in combination with lithium or sodium valproate) and… Jul 2011 Recommended with restriction unclear
quetiapine Maintenance treatment of bipolar I disorder as monotherapy. The submission also requested a broader listing for treatment of bipolar disorder more generally,… Jul 2010 Recommended with restriction no section in document
quetiapine Maintenance treatment of bipolar I disorder as monotherapy. The submission also requested a broader listing for treatment of bipolar disorder, but PBAC… Jul 2010 Recommended with restriction no section in document
quetiapine fumarate Maintenance treatment of bipolar I disorder, in combination with lithium or sodium valproate, for the prevention of recurrence of manic, depressive or mixed… Mar 2009 Recommended with restriction no section in document
ziprasidone hydrochloride Monotherapy, for up to 6 months, of an episode of acute mania or mixed episodes associated with bipolar I disorder. Nov 2008 Recommended with restriction no section in document

What the PBS pays

$117M in government benefit over 2024–25, across 2,452,495 services.

This is spend on the medicines considered for this condition, not spend on the disease. A medicine used for several conditions is counted in full under each, so figures across conditions add to more than national PBS expenditure.

MedicineGovernment benefit
aripiprazole $72.4M
quetiapine $19.3M
quetiapine fumarate $19.3M
asenapine $3.7M
ziprasidone hydrochloride $2.3M

Appraised elsewhere

NICE, in England and Wales, has appraised 1 technology for this condition, recommending 1 . A different committee, a different population and a different price: this is what has been looked at there, not a verdict on what happened here.

TechnologyAppraisalOutcomeDate
aripiprazoleAripiprazole for treating moderate to severe manic episodes in adolescents with bipolar I disorder TA292 recommended 2013-07

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 0 of 2 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.