Disease index

amyotrophic lateral sclerosis

Neurology · 2018–2026

7decisions
3medicines
5carried consumer input
135individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
riluzole Treatment of amyotrophic lateral sclerosis (ALS), specifically for patients with swallowing difficulties and/or requiring percutaneous endoscopic gastrostomy… Mar 2026 Noted none received
tofersen Treatment of amyotrophic lateral sclerosis (ALS) associated with a mutation in the superoxide dismutase 1 (SOD1) gene. Mar 2026 Recommended with restriction 33 individuals
edaravone Treatment of amyotrophic lateral sclerosis (ALS) in adults who are independent in activities of daily living, have normal respiratory function, and where… Dec 2025 Noted no section in document
tofersen Adjunct treatment to best supportive care with or without riluzole in patients with amyotrophic lateral sclerosis (ALS) who have a superoxide dismutase 1… Nov 2025 Not recommended 33 individuals Motor Neuron Disease Australia
edaravone Adjunct treatment to current standard of care with or without riluzole in patients with amyotrophic lateral sclerosis (ALS) who are independent in activities… Mar 2024 Recommended with restriction 54 individuals Motor Neurone Disease Australia
edaravone Adjunct treatment to standard of care with or without riluzole in patients with amyotrophic lateral sclerosis (ALS). Nov 2023 Not recommended 15 individuals Motor Neurone Disease Australia
riluzole Treatment of amyotrophic lateral sclerosis (ALS) in patients diagnosed by a neurologist with disease duration ≤5 years, FVC ≥60% predicted, and meeting… Nov 2018 Noted input received Motor Neurone Disease Australia · MND Australia

Who spoke

Motor Neurone Disease Australia · MND Australia · Motor Neuron Disease Australia

What the PBS pays

$2M in government benefit over 2024–25, across 12,778 services.

This is spend on the medicines considered for this condition, not spend on the disease. A medicine used for several conditions is counted in full under each, so figures across conditions add to more than national PBS expenditure.

MedicineGovernment benefit
riluzole $1.8M
edaravone $0M

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 5 of 7 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.