Disease index

age-related macular degeneration

Ophthalmology · 2007–2025

8decisions
3medicines
2carried consumer input
0individual submissions

Every decision

MedicineMeetingOutcomeConsumer input
aflibercept Biosimilar to Eylea for the same indications (not specified in detail in this PSD, as it is a Category 3 biosimilar submission). Jul 2025 Recommended none received
aflibercept Treatment of subfoveal choroidal neovascularisation (CNV) secondary to age-related macular degeneration (AMD), specifically neovascular age-related macular… Nov 2024 Recommended with restriction none received
brolucizumab Treatment of subfoveal choroidal neovascularisation (CNV) due to age-related macular degeneration (AMD). Jul 2020 Recommended with restriction input received
brolucizumab Treatment of subfoveal choroidal neovascularisation (CNV) due to age-related macular degeneration (AMD). Nov 2019 Not recommended input received Macular Disease Foundation Australia
aflibercept Initial and continuing treatment of subfoveal choroidal neovascularisation (CNV) due to age-related macular degeneration (AMD), as diagnosed by fluorescein… Mar 2012 Recommended with restriction unclear
aflibercept Initial and continuing treatment of subfoveal choroidal neovascularisation (CNV) due to age-related macular degeneration (wet AMD), as diagnosed by fluorescein… Mar 2012 Recommended with restriction unclear
ranibizumab Treatment of subfoveal choroidal neovascularisation (CNV) due to age-related macular degeneration (AMD), administered by intravitreal injection. Mar 2007 Recommended with restriction no section in document
ranibizumab Treatment of subfoveal choroidal neovascularisation (CNV) due to age-related macular degeneration (AMD). The indication encompasses predominantly classic… Mar 2007 Recommended with restriction no section in document

Who spoke

Macular Disease Foundation Australia

What the PBS pays

$599M in government benefit over 2024–25, across 620,356 services.

This is spend on the medicines considered for this condition, not spend on the disease. A medicine used for several conditions is counted in full under each, so figures across conditions add to more than national PBS expenditure.

MedicineGovernment benefit
aflibercept $506.1M
ranibizumab $91.6M
brolucizumab $1.5M

Appraised elsewhere

NICE, in England and Wales, has appraised 1 technology for this condition, recommending 1 . A different committee, a different population and a different price: this is what has been looked at there, not a verdict on what happened here.

TechnologyAppraisalOutcomeDate
ranibizumab and pegaptanibRanibizumab and pegaptanib for the treatment of age-related macular degeneration TA155 recommended 2008-08

Conditions are classified by a language model from the indication text of each submission, so an individual label here can be wrong. Consumer input is read from the document's own consumer comments section: 2 of 4 decisions since 2014 carried some. Silence means no comment reached the committee through that facility, not that nobody was affected. More on how this was built.